Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Coagulation, inflammation, and hyperplasia frequently restrict the effectiveness of
cardiovascular stents. It is critical to modify stent surfaces to allow for in situ tissue healing …

Valvular heart disease (VHD), clinically manifested as stenosis and regurgitation of native
heart valve, is one of the most prevalent cardiovascular diseases with high mortality. Heart …

Glutaraldehyde crosslinked biological heart valves (BHVs) are increasingly implanted with
development of transcatheter heart valve implantation. While poor cytocompatibility and …

The durability of the current polymeric heart valves remains to be improved, which has
proven to be highly dynamics and species dependent. Herein, inspired by the fiber …

Stem cell spheroids possess higher viability and up-regulated paracrine function, showing
advanced curative effect. However, the barrier of efficient spheroids preparation and …

In recent years, bioprosthetic heart valves (BHVs) prepared by cross-linking porcine or
bovine pericardium with glutaraldehyde (Glut) have received widespread attention due to …

Bioprosthetic heart valves (BHVs) have been widely used due to the revolutionary
transcatheter aortic valve replacement (TAVR) techniques but suffer from a limited lifespan …

ABSTRACT Currently, glutaraldehyde (GA)-crosslinked bioprosthetic heart valves (BHVs)
still do not guarantee good biocompatibility and long-term effective durability for clinical …

The present study describes the preparation of woven silk fabric (WSF) and poly (ethylene
glycol) diacrylate (PEGDA) hydrogel composite reinforced artificial heart valve (SPAHV) …