Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Recent advances in small-molecule fluorescent probes for diagnosis of cancer cells/tissues

K Wang, C Liu, H Zhu, Y Zhang, M Su, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Cancer has always been covetous to the health of human beings, and countless people die
every year due to cancer. Accurate diagnosis of cancer is an important prerequisite for its …

Diketopyrrolopyrrole-based fluorescent probe for visualizing over-expressed carboxylesterase in fever via ratiometric imaging

B Zhang, S Qin, N Wang, X Lu, J Jiao, J Zhang, W Zhao - Talanta, 2024 - Elsevier
Fever is the result of inflammation and the innate self-defense response of organisms, can
cause abnormal changes in the activity of many enzymes in organisms, including the …

Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO, Viscosity, and Polarity and Its Application in Ferroptosis and Cancer Models

L Fan, Q Yang, Q Zan, K Zhao, W Lu, X Wang… - Analytical …, 2023 - ACS Publications
Intracellular peroxynitrite anions (ONOO–) and microenvironments (such as viscosity and
polarity) play an important role in maintaining redox homeostasis, regulating diffusion …

Selective visualization of tumor cell membranes and tumors with a viscosity-sensitive plasma membrane probe

Q Li, W Zhu, S Gong, S Jiang, G Feng - Analytical Chemistry, 2023 - ACS Publications
Cancer is a worldwide health problem. Revealing the changes in the microenvironment after
cell carcinogenesis is helpful to understand cancer and develop sensitive methods for …

Dual-channel fluorescent probe for simultaneously detecting H2S and viscosity/polarity and its application in non-alcoholic fatty liver, tumor tissue, and food spoilage

Q Zan, L Fan, L Ma, Q Yang, K Zhao, Y Huang… - Sensors and Actuators B …, 2023 - Elsevier
Intracellular hydrogen sulfide (H 2 S) and micro-environments (eg viscosity and polarity) are
tightly correlated with various physiological/pathological processes, making them potential …

Recent advance in the development of the fluorescent responsive probes for the study of ferroptosis

B Dong, S Li, Y Wang, X Tang, R Wang, X Kong… - TrAC Trends in …, 2023 - Elsevier
Ferroptosis is an iron-dependent cell death form with the characteristic of the excessive
accumulation of lipid peroxidation. In recent ten years, a host of researches suggested that …

Bichromatic imaging with hemicyanine fluorophores enables simultaneous visualization of non-alcoholic fatty liver disease and metastatic intestinal cancer

W Xu, S Liu, Z Chen, F Wu, W Cao, Y Tian… - Analytical …, 2022 - ACS Publications
Simultaneous detection of different diseases via a single fluorophore is challenging. We
herein report a bichromatic fluorophore named Cy-914 for the simultaneous diagnosis of …

A novel activatable fluorescent probe for revealing the dynamic of esterase and viscosity during ferroptosis and DILI

J Liu, X Xu, P Xie, X Yang, Y Ye, Y Zhao - Sensors and Actuators B …, 2023 - Elsevier
Esterase, a hydrolase, is present in a vast variety of animals, plants, and microbes. It has the
potential to promote the hydrolysis of diverse esters while also could function as a valid …