[HTML][HTML] The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases

Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …

[HTML][HTML] Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

Nrf2: a dark horse in Alzheimer's disease treatment

A Osama, J Zhang, J Yao, X Yao, J Fang - Ageing research reviews, 2020 - Elsevier
Abstract Alzheimer's disease (AD), an age-dependent neurodegenerative disorder, is the
main cause of dementia. Common hallmarks of AD include the amyloid β-peptide (Aβ) …

[HTML][HTML] The potential of flavonoids for the treatment of neurodegenerative diseases

P Maher - International journal of molecular sciences, 2019 - mdpi.com
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), currently affect more …

[HTML][HTML] Neuroprotection against oxidative stress: Phytochemicals targeting TrkB signaling and the Nrf2-ARE antioxidant system

MA Hannan, R Dash, AAM Sohag… - Frontiers in Molecular …, 2020 - frontiersin.org
Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …

Health functionality of apigenin: A review

F Ali, Rahul, F Naz, S Jyoti… - International Journal of …, 2017 - Taylor & Francis
Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

[HTML][HTML] Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

[HTML][HTML] Phytochemicals and cognitive health: Are flavonoids doing the trick?

I Bakoyiannis, A Daskalopoulou, V Pergialiotis… - Biomedicine & …, 2019 - Elsevier
Flavonoids constitute a large group of polyphenolic compounds with numerous effects on
behaviour and cognition. These effects vary from learning and memory enhancement to an …