The adverse-effect profile of lacosamide

J Li, M Sun, X Wang - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Introduction: Lacosamide has been used in epilepsy patients in the United States, Europe
and Asia since it was approved by the FDA in 2008. Many patients have benefited from this …

Antiseizure medication-induced alopecia: a literature review

J Pitton Rissardo, AL Fornari Caprara, M Casares… - Medicines, 2023 - mdpi.com
Background: Adverse effects of antiseizure medications (ASMs) remain one of the major
causes of non-adherence. Cosmetic side effects (CSEs) are among the most commonly …

Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3 …

M Baulac, F Rosenow, M Toledo, K Terada… - The Lancet …, 2017 - thelancet.com
Background Further options for monotherapy are needed to treat newly diagnosed epilepsy
in adults. We assessed the efficacy, safety, and tolerability of lacosamide as a first-line …

BRIVA‐LIFE–A multicenter retrospective study of the long‐term use of brivaracetam in clinical practice

V Villanueva, FJ López‐González… - Acta neurologica …, 2019 - Wiley Online Library
Objectives Evaluate long‐term effectiveness and tolerability of brivaracetam in clinical
practice in patients with focal epilepsy. Materials and Methods This was a multicenter …

Adjunctive brivaracetam in focal epilepsy: real-world evidence from the BRIVAracetam add-on First Italian netwoRk STudy (BRIVAFIRST)

S Lattanzi, L Canafoglia, MP Canevini, S Casciato… - CNS drugs, 2021 - Springer
Background In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure
frequency in patients with drug-resistant focal epilepsy. Studies performed in a naturalistic …

Efficacy and tolerability of adjunctive lacosamide in pediatric patients with focal seizures

V Farkas, B Steinborn, JR Flamini, Y Zhang, N Yuen… - Neurology, 2019 - AAN Enterprises
Objective To evaluate efficacy and tolerability of adjunctive lacosamide in children and
adolescents with uncontrolled focal (partial-onset) seizures. Methods In this double-blind …

PROVE: Retrospective, non‐interventional, Phase IV study of perampanel in real‐world clinical care of patients with epilepsy

RT Wechsler, J Wheless, M Zafar… - Epilepsia …, 2022 - Wiley Online Library
Objective To assess retention, dosing, efficacy, and safety of perampanel in a large cohort of
patients with epilepsy during routine clinical care. Methods PROVE was a retrospective, non …

Real-world safety of Lacosamide: A pharmacovigilance study based on spontaneous reports in the FDA adverse event reporting system

P Liu, M He, X Xu, Y He, W Yao, B Liu - Seizure: European Journal of …, 2023 - Elsevier
Introduction Lacosamide is licensed for the treatment of focal seizures in both adults and
children, however there is little information available on its adverse reactions. Using the FDA …

Effectiveness and tolerability of lacosamide as add‐on therapy in patients with brain tumor–related epilepsy: Results from a prospective, noninterventional study in …

R Rudà, C Houillier, M Maschio, JC Reijneveld… - …, 2020 - Wiley Online Library
Objective To evaluate the effectiveness and tolerability of lacosamide added to one or two
antiepileptic drugs (AEDs) in the treatment of patients with brain tumor–related epilepsy …

Lacosamide in patients with gliomas and uncontrolled seizures: results from an observational study

R Rudà, A Pellerino, F Franchino, C Bertolotti… - Journal of neuro …, 2018 - Springer
To report the efficacy and tolerability of lacosamide as an add-on treatment in patients with
gliomas and uncontrolled seizures despite conventional antiepileptic drugs (AEDs). We …