The number of cancer cases worldwide keeps growing unstoppably, despite the undeniable
advances achieved by basic research and clinical practice. Urologic tumors, including some …

Urothelial bladder cancer (UBC) is one of the most prevalent and aggressive malignancies.
Recent evidence indicates that the tumor microenvironment (TME), including a variety of …

Background and objective In comparison to chemotherapy, enfortumab vedotin (EV)
prolonged overall survival in patients with previously treated advanced urothelial carcinoma …

In recent years the introduction of immunotherapy has importantly changed the treatment
landscape of advanced urothelial carcinoma. Several immune checkpoint inhibitors are now …

Bladder cancer is one of the most frequent malignant tumors of the urinary system. The
prevalence of bladder cancer among men and women is roughly 5: 2, and both its incidence …

Molecular subtypes of muscle-invasive bladder cancer (MIBC) display differential survival
and drug sensitivities in clinical trials. To date, they have not been used as a paradigm for …

Purpose To evaluate the expression levels of spalt-like transcription factor 4 (SALL4) in
bladder urothelial carcinoma, and determine its role and underlying mechanism of action in …