Imperative role of machine learning algorithm for detection of Parkinson's disease: review, challenges and recommendations

A Rana, A Dumka, R Singh, MK Panda, N Priyadarshi… - Diagnostics, 2022 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disease that affects the neural, behavioral,
and physiological systems of the brain. This disease is also known as tremor. The common …

Does exercise attenuate disease progression in people with Parkinson's disease? A systematic review with meta-analyses

JA Li, MB Loevaas, C Guan, L Goh… - … and Neural Repair, 2023 - journals.sagepub.com
Introduction Exercise has many benefits for people with Parkinson's disease (PD) and has
been suggested to modify PD progression, but robust evidence supporting this is lacking …

Targeting Nrf2 signaling pathway and oxidative stress by resveratrol for Parkinson's disease: an overview and update on new developments

MY Zamanian, RMR Parra, A Soltani… - Molecular Biology …, 2023 - Springer
Parkinson's disease (PD) as a prevalent neurodegenerative condition impairs motor function
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …

Gait speed in clinical and daily living assessments in Parkinson's disease patients: performance versus capacity

A Atrsaei, MF Corrà, F Dadashi, N Vila-Chã… - npj Parkinson's …, 2021 - nature.com
Gait speed often referred as the sixth vital sign is the most powerful biomarker of mobility.
While a clinical setting allows the estimation of gait speed under controlled conditions that …

The role of oxidative stress in Parkinson's disease

KH Chang, CM Chen - Antioxidants, 2020 - mdpi.com
Parkinson's disease (PD) is caused by progressive neurodegeneration of dopaminergic
(DAergic) neurons with abnormal accumulation of α-synuclein in substantia nigra (SN) …

Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases

M Luo, LKC Lee, B Peng, CHJ Choi… - Advanced …, 2022 - Wiley Online Library
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …

Deep brain stimulation beyond the clinic: Navigating the future of Parkinson's and Alzheimer's disease therapy

DKL Senevirathne, A Mahboob, K Zhai, P Paul… - Cells, 2023 - mdpi.com
Deep brain stimulation (DBS) is a surgical procedure that uses electrical neuromodulation to
target specific regions of the brain, showing potential in the treatment of neurodegenerative …

Integration of miRNA's theranostic potential with nanotechnology: promises and challenges for Parkinson's disease therapeutics

KP Tryphena, G Singh, N Jain, P Famta… - Mechanisms of Ageing …, 2023 - Elsevier
Despite the wide research going on in Parkinson's disease (PD), the burden of PD still
remains high and continues to increase. The current drugs available for the treatment of PD …

[HTML][HTML] The role of cannabidiol in aging

B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …

Estrogenic plants: to prevent neurodegeneration and memory loss and other symptoms in women after menopause

V Echeverria, F Echeverria, GE Barreto… - Frontiers in …, 2021 - frontiersin.org
In mammals, sexual hormones such as estrogens play an essential role in maintaining brain
homeostasis and function. Estrogen deficit in the brain induces many undesirable symptoms …