Clostridioides difficile phage biology and application
J Heuler, LC Fortier, X Sun - FEMS Microbiology Reviews, 2021 - academic.oup.com
Clostridium difficile, now reclassified as Clostridioides difficile, is the causative agent of C.
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …
A review of Clostridioides difficile infection and antibiotic-associated diarrhea
Antibiotic-associated diarrhea (AAD) is defined as diarrhea associated with antibiotic
exposure, either while on antibiotics, or for up to 8 weeks after antibiotic discontinuation. 1, 2 …
exposure, either while on antibiotics, or for up to 8 weeks after antibiotic discontinuation. 1, 2 …
An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium
M Fuchs, V Lamm-Schmidt, J Sulzer… - Proceedings of the …, 2021 - National Acad Sciences
The gram-positive human pathogen Clostridioides difficile has emerged as the leading
cause of antibiotic-associated diarrhea. However, little is known about the bacterium's …
cause of antibiotic-associated diarrhea. However, little is known about the bacterium's …
Treatment of Clostridioides (Clostridium) difficile infection
O Jarmo, A Veli-Jukka, M Eero - Annals of medicine, 2020 - Taylor & Francis
Clostridioides (formerly: Clostridium) difficile infection (CDI) is a major cause of diarrhoea for
inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of …
inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of …
Recurrent Clostridioides difficile Infection: Current Clinical Management and Microbiome-Based Therapies
P Berry, S Khanna - BioDrugs, 2023 - Springer
Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea.
The high incidence and recurrence rates of C. difficile infection, as well as its associated …
The high incidence and recurrence rates of C. difficile infection, as well as its associated …
Effects of probiotics BaSC06 on intestinal digestion and absorption, antioxidant capacity, microbiota composition, and macrophage polarization in pigs for fattening
X Cao, L Tang, Z Zeng, B Wang, Y Zhou… - Frontiers in Veterinary …, 2020 - frontiersin.org
This study aimed to compare the effects of BaSC06 and antibiotics on growth, digestive
functions, antioxidant capacity, macrophage polarization, and intestinal microbiota of pigs for …
functions, antioxidant capacity, macrophage polarization, and intestinal microbiota of pigs for …
Towards Development of a Non-Toxigenic Clostridioides difficile Oral Spore Vaccine against Toxigenic C. difficile
J Hughes, C Aston, ML Kelly, R Griffin - Pharmaceutics, 2022 - mdpi.com
Clostridioides difficile is an opportunistic gut pathogen which causes severe colitis, leading
to significant morbidity and mortality due to its toxins, TcdA and TcdB. Two intra-muscular …
to significant morbidity and mortality due to its toxins, TcdA and TcdB. Two intra-muscular …
The (p) ppGpp synthetase RSH mediates stationary-phase onset and antibiotic stress survival in Clostridioides difficile
The human pathogen Clostridioides difficile is increasingly tolerant of multiple antibiotics
and causes infections with a high rate of recurrence, creating an urgent need for new …
and causes infections with a high rate of recurrence, creating an urgent need for new …
Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin
K Ernst, M Landenberger, J Nieland, K Nørgaard… - Toxins, 2021 - mdpi.com
The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that
cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main …
cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main …
Mucosal Vaccination Strategies against Clostridioides difficile Infection
Clostridioides difficile infection (CDI) presents a major public health threat by causing
frequently recurrent, life-threatening cases of diarrhea and intestinal inflammation. The …
frequently recurrent, life-threatening cases of diarrhea and intestinal inflammation. The …