Glial cells which are indispensable for the central nervous system development and
functioning, are proven to be vulnerable to a harmful influence of pathological cues and …

Astrocytes, the most abundant glial cells in the central nervous system (CNS), have
numerous integral roles in all CNS functions. They are essential for synaptic transmission …

During development, oligodendrocytes and Schwann cells myelinate central and peripheral
nervous system axons, respectively, while motor exit point (MEP) glia are neural tube …

The past 15–20 years has seen a remarkable shift in our understanding of astrocyte
contributions to central nervous system (CNS) function. Astrocytes have emerged from the …

In response to central nervous system (CNS) injury, astrocytes go through a series of
alterations, referred to as reactive astrogliosis, ranging from changes in gene expression …

Introduction Alzheimer's disease (AD) is the most frequent cause of dementia and still lacks
effective therapy. Clinical signs of AD include low levels of endogenous melanocortins …

Alzheimer's disease has been considered mostly as a neuronal pathology, although
increasing evidence suggests that glial cells might play a key role in the disease onset and …

Olig2 is a basic helix–loop–helix transcription factor that plays a critical role in the central
nervous system. It directs the specification of motor neurons and oligodendrocyte precursor …

In the mammalian cerebral neocortex, different regions have different cytoarchitecture,
neuronal birthdates, and functions. In most regions, neuronal migratory profiles are …

Glial fibrillary acidic protein (GFAP) is commonly used as a specific marker for the
identification of astrocytes. Nevertheless, it is known from the literature that astrocytes in situ …