Parkinson's disease (PD) is a neurodegenerative disease with an increased morbidity. The
pathogenesis PD has not been fully elucidated, and whatever mechanism is involved, it …

Parkinson's disease (PD) is a neurodegenerative condition characterized by the loss of
midbrain dopaminergic neurons, leading to motor symptoms. While current treatments …

Amyloid diseases have become a global concern due to their increasing prevalence.
Transition metals, including copper, can affect the aggregation of the pathological proteins …

Abstract Brain Organiods (BOs) are a promising technique for researching disease
progression in the human brain. These organoids, which are produced from human induced …

Midbrain dopaminergic (mDA) neurons are significantly impaired in patients inflicted with
Parkinson's disease (PD), subsequently affecting a variety of motor functions. There are four …

Mitochondrial diseases are difficult to treat due to the complexity and multifaceted nature of
mitochondrial dysfunction. Brain organoids are three-dimensional (3D) structures derived …

Parkinson's disease (PD), a progressive neurodegenerative disease, has no cure, and
current therapies are not effective at halting disease progression. The disease affects mid …

Parkinson's disease (PD) is one of the most devastating neurological diseases; however,
there is no effective cure yet. The availability of human induced pluripotent stem cells …

This review delves into the groundbreaking impact of induced pluripotent stem cells (iPSCs)
and three-dimensional organoid models in propelling forward neuropathology research …

Human brain development is spatially and temporally complex. Insufficient access to human
brain tissue and inadequacy of animal models have limited the study of brain development …