The chemokine CXC-ligand 13 (CXCL13) is a major B cell chemoattractant to B cell follicles
in secondary lymphoid organs (SLO) that proposedly recruits B cells to the cerebrospinal …

Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …

Castleman disease (CD) is a rare lymphoproliferative disorder. Among subtypes of CD,
idiopathic multicentric CD-not otherwise specified (iMCD-NOS) has a poor prognosis and its …

The autoimmune diseases of the central nervous system (CNS) represent individual
heterogeneity with different disease entities. Although clinical and imaging features make it …

Multiple sclerosis (MS) is an immune-mediated inflammatory and degenerative disorder of
the central nervous system (CNS) with heterogeneous clinical manifestations. In the last …

The most recent and promising therapeutic strategies for inflammatory bowel disease (IBD)
have engaged biologics targeting single effector components involved in major steps of the …

Abstract Chemokine receptor 7 (CCR7) is a G protein-coupled receptor containing 7
transmembrane domains that is expressed on various cells, such as naive T/B cells, central …

Tertiary lymphoid structure (TLS) represents lymphocyte clusters in non-lymphoid organs.
The formation and maintenance of TLS are dependent on follicular helper T (TFH) cells …

Background As Systemic Sclerosis (SSc) is a connective tissue ailment that impacts various
bodily systems. The study aims to clarify the molecular subtypes of SSc, with the ultimate …

Introduction Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease that
presents a challenge for clinicians. To identify potential biomarkers for diagnosis and …