Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Importance Alzheimer disease (AD) is now known to have a long preclinical phase in which
pathophysiologic processes develop many years, even decades, before the onset of clinical …

We recently reported that serum methylglyoxal (sMG) is associated with a faster rate of
decline in a global measure of cognition in the very elderly. We here provide for the first time …

Since the publication of the latest recommendations for the diagnosis and treatment of
Vascular Dementia by the Brazilian Academy of Neurology in 2011, significant advances on …

Background Hypothalamic-pituitary-adrenal axis dysregulation, which is typically assessed
by measuring cortisol levels, is associated with cognitive dysfunction, hippocampal atrophy …

ABSTRACT Background/Aims: The issue of whether sex offenders have cognitive deficits
remains controversial. The objective of this study was to compare the neuropsychological …

Background The deterioration of the central cholinergic system in aging is hypothesized to
underlie declines in several cognitive domains, including memory and executive functions …

Vascular dementia (VaD) is the most prevalent form of secondary dementia and the second
most common of all dementias. The present paper aims to define guidelines on the basic …

ABSTRACT “Normal” age-related cognitive decline has been associated with cardiovascular
risk factors. Framingham Vascular Age is age-normed cardiovascular risk which may help …

Desde a publicação das últimas recomendações para o diagnóstico e tratamento da
Demência Vascular pela Academia Brasileira de Neurologia em 2011, avanços …