Eicosapentaenoic acid and docosahexaenoic acid from fish oil and their role in cancer research

W Ashfaq, K Rehman, MI Siddique… - Food Reviews …, 2020 - Taylor & Francis
Omega-3 fatty acids are long chain polyunsaturated fatty acids (LCPUFAs) have been the
source of interest because of their beneficial pharmacological activities. These omega 3 …

Decreased severity of ovarian cancer and increased survival in hens fed a flaxseed-enriched diet for 1 year

K Ansenberger, C Richards, Y Zhuge, A Barua… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: With the exception of the laying hen, no other animal model of spontaneous
ovarian surface epithelial cancer replicates the human disease. Flaxseed is the richest …

Avian biomodels for use as pharmaceutical bioreactors and for studying human diseases

G Song, JY Han - Annals of the New York Academy of …, 2011 - Wiley Online Library
Animal‐based biotechnologies involve the use of domestic animals for the production of
pharmaceuticals and various proteins in milk and eggs, as disease models, as tools for stem …

Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner

A Dikshit, MA Gomes Filho, E Eilati, S McGee… - British Journal of …, 2015 - cambridge.org
The objective of the present study was to find the optimum dose of flaxseed that would
decrease PG and alter oestrogen pathway endpoints implicated in ovarian cancer. In the …

[HTML][HTML] Correlation analysis and clinical significance of CA125, HE4, DDI, and FDP in type II epithelial ovarian cancer

L Qiao, X Chen, X Xi, X Chen, P Zhang, H Dong, X Wu… - Medicine, 2020 - journals.lww.com
Ovarian cancer is one of the common female malignant tumors. The early diagnosis and
treatment of ovarian cancer has been a research hotspot. Therefore, we aimed to investigate …

Chicken pleiotrophin: regulation of tissue specific expression by estrogen in the oviduct and distinct expression pattern in the ovarian carcinomas

JY Lee, W Jeong, W Lim, J Kim, FW Bazer, JY Han… - PloS one, 2012 - journals.plos.org
Pleiotrophin (PTN) is a developmentally-regulated growth factor which is widely distributed
in various tissues and also detected in many kinds of carcinomas. However, little is known …

Expression and regulation of beta-defensin 11 in the oviduct in response to estrogen and in ovarian tumors of chickens

W Lim, W Jeong, J Kim, Y Yoshimura, FW Bazer… - Molecular and Cellular …, 2013 - Elsevier
Avian beta-defensins (AvBDs), also known as gallinacins, are small cationic peptides having
three cysteine disulfide bonds between their cysteine residues. They play essential roles in …

Hypermethylation and post-transcriptional regulation of DNA methyltransferases in the ovarian carcinomas of the laying hen

JY Lee, W Jeong, W Lim, CH Lim, SM Bae, J Kim… - PloS one, 2013 - journals.plos.org
DNA methyltransferases (DNMTs) are key regulators of DNA methylation and have crucial
roles in carcinogenesis, embryogenesis and epigenetic modification. In general, DNMT1 …

Dynamics of the primate ovarian surface epithelium during the ovulatory menstrual cycle

JW Wright, L Jurevic, RL Stouffer - Human reproduction, 2011 - academic.oup.com
BACKGROUND Epithelial ovarian cancer (EOC) risk correlates strongly with the number of
ovulations that a woman experiences. The primary source of EOC in women is the ovarian …

Prostaglandin D2 synthase related to estrogen in the female reproductive tract

W Lim, SM Bae, G Jo, FW Bazer, Y Choi… - … and biophysical research …, 2015 - Elsevier
Abstract Prostaglandin D 2 synthase (PTGDS), also known as a glutathione-independent
prostaglandin D synthase, catalyzes prostaglandin H 2 to prostaglandin D 2 that exhibits …