Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular …

Q Wu, X Li, M Long, X Xie, Q Liu - Scientific Reports, 2023 - nature.com
Histone lysine lactylation (Kla) plays a vital role in the tumorigenesis of hepatocellular
carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic …

[HTML][HTML] Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Bioinformatics and the Role of NR6A1 in the Progression of HCC

ZH Lin, J Zhang, LK Zhuang, YN Xin… - Journal of Clinical and …, 2022 - ncbi.nlm.nih.gov
Methods Bioinformatics analysis using The Cancer Genome Atlas and ImmPort databases
was used to identify IR-DEGs. Lasso Cox regression and multivariate Cox regression …

General features and novel gene signatures that identify Epstein-Barr virus-associated epithelial cancers

C Heawchaiyaphum, C Pientong, H Yoshiyama… - Cancers, 2021 - mdpi.com
Simple Summary Nasopharyngeal carcinoma (NPC), Epstein-Barr virus (EBV)-associated
gastric carcinoma (EBVaGC), and oral squamous cell carcinoma (OSCC) are epithelial …

[HTML][HTML] Identification of most representative hub-genes for diagnosis, prognosis, and therapies of hepatocellular carcinoma

MA Hossen, MS Reza, MM Rana… - Chinese Clinical …, 2024 - cco.amegroups.org
Background: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related
deaths globally. To reduce HCC-related mortality, early diagnosis and therapeutic …