Depression is a prevalent psychiatric disorder that often leads to poor quality of life and
impaired functioning. Treatment during the acute phase of a major depressive episode aims …

Introduction Combinations of psychotherapy with antidepressants are gold-standard
psychiatric treatments. They operate through complex and interactional mechanisms, not …

Patients with mental disorders have an increased risk to develop cardiovascular disease
(CVD), and CVD are frequently comorbid with especially adjustment, anxiety and depressive …

Background: Schizophrenia is a complex illness in which genetic, environmental, and
epigenetic components have been implicated. However, recently, psychiatric disorders …

Abstract Background Major Depressive Disorder (MDD) is a complex disease characterized
by emotional, physical and cognitive symptoms. We explored the efficacy of vortioxetine …

Abstract Major Depressive Episodes (MDE) following COVID-19 are frequent, can have a
characteristic clinical picture, and are associated with immune-inflammatory changes …

Depression is the most commonly experienced mood state over the life span in individuals
with bipolar disorder (BD) and is the primary driver of functional impairment and suicidality in …

Depressed patients and their physicians naturally expect that each new antidepressant that
reaches the market will represent a conceptual and therapeutic advance over previous …

A growing body of evidence supports the idea that drugs targeting the glutamate system may
represent a valuable therapeutic alternative in major depressive disorders (MDD). The rapid …

Cardio-vascular diseases (CVDs) and CVD-related disorders (including cerebrovascular
diseases; CBVDs) are a major public health concern as they represent the leading cause of …