Lipid droplets: A cellular organelle vital in cancer cells

Y Jin, Y Tan, J Wu, Z Ren - Cell death discovery, 2023 - nature.com
Lipid droplets (LDs) are cellular organelles comprising a core of neutral lipids (glycerides,
sterols) encased within a single phospholipid membrane, responsible for storing surplus …

Emerging approaches for restoration of hearing and vision

S Kleinlogel, C Vogl, M Jeschke, J Neef… - Physiological …, 2020 - journals.physiology.org
Impairments of vision and hearing are highly prevalent conditions limiting the quality of life
and presenting a major socioeconomic burden. For a long time, retinal and cochlear …

Lipid droplets as endogenous intracellular microlenses

X Chen, T Wu, Z Gong, J Guo, X Liu, Y Zhang… - Light: Science & …, 2021 - nature.com
Using a single biological element as a photonic component with well-defined features has
become a new intriguing paradigm in biophotonics. Here we show that endogenous lipid …

Endowing a plain fluidic chip with micro-optics: a holographic microscope slide

V Bianco, B Mandracchia, V Marchesano… - Light: Science & …, 2017 - nature.com
Abstract Lab-on-a-Chip (LoC) devices are extremely promising in that they enable
diagnostic functions at the point-of-care. Within this scope, an important goal is to design …

Quantitative phase imaging (QPI) in neuroscience

C Hu, G Popescu - IEEE Journal of Selected Topics in Quantum …, 2018 - ieeexplore.ieee.org
Quantitative phase imaging (QPI) is an emerging label-free modality that attracts significant
interest in biomedicine in general and neuroscience in particular. Based on the principle of …

Super-resolution three-dimensional fluorescence and optical diffraction tomography of live cells using structured illumination generated by a digital micromirror device

S Shin, D Kim, K Kim, YK Park - Scientific reports, 2018 - nature.com
We present a multimodal approach for measuring the three-dimensional (3D) refractive
index (RI) and fluorescence distributions of live cells by combining optical diffraction …

Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis

D Li, N Wang, T Zhang, G Wu, Y Xiong… - Advanced …, 2022 - spiedigitallibrary.org
The achievement of functional nanomodules for subcellular label-free measurement has
long been pursued in order to fully understand cellular functions. Here, a compact label-free …

[HTML][HTML] Microsphere-assisted quantitative phase microscopy: a review

V Abbasian, T Pahl, L Hüser, S Lecler… - Light: Advanced …, 2024 - light-am.com
Light microscopes are the most widely used devices in life and material sciences that allow
the study of the interaction of light with matter at a resolution better than that of the naked …

Multiparametric quantitative phase imaging for real-time, single cell, drug screening in breast cancer

ER Polanco, TE Moustafa, A Butterfield… - Communications …, 2022 - nature.com
Quantitative phase imaging (QPI) measures the growth rate of individual cells by quantifying
changes in mass versus time. Here, we use the breast cancer cell lines MCF-7, BT-474, and …

Real-time halo correction in phase contrast imaging

ME Kandel, M Fanous, C Best-Popescu… - Biomedical optics …, 2018 - opg.optica.org
As a label-free, nondestructive method, phase contrast is by far the most popular microscopy
technique for routine inspection of cell cultures. However, features of interest such as …