DNA methylation (DNAme) and histone post-translational modifications (PTMs) have
important roles in transcriptional regulation. Although many reports have characterized the …

Methylation of cytosine in CpG dinucleotides and histone lysine and arginine residues is a
chromatin modification that critically contributes to the regulation of genome integrity …

DNA methylation plays a vital role in epigenetic regulation in both plants and animals, and
typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …

Salt and drought stress are major environmental issues world-widely. These stresses can
result in failures of seed germination, limiting agricultural production. New approaches are …

During postnatal development, the DNA methyltransferase DNMT3A deposits high levels of
non-CG cytosine methylation in neurons. This methylation is critical for transcriptional …

Although extended pluripotent stem cells (EPSCs) have the potential to form both embryonic
and extraembryonic lineages, how their transcriptional regulatory mechanism differs from …

Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

APS (antiphospholipid syndrome) is a systematic autoimmune disease accompanied with
venous or arterial thrombosis and poor pregnant manifestations, partly attributing to the …

The recent deluge of genome-wide technologies for the mapping of the epigenome and
resulting data in cancer samples has provided the opportunity for gaining insights into and …

Background DNA hypermethylation at promoter CpG islands (CGIs) is a hallmark of cancers
and could lead to dysregulation of gene expression in the development of cancers, however …