[HTML][HTML] The H3. 3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation

J Sinha, JF Nickels, AR Thurm, CH Ludwig… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Histone H3. 3 is frequently mutated in cancers, with the lysine 36 to methionine mutation
(K36M) being a hallmark of chondroblastomas. While it is known that H3. 3K36M changes …

Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization

A Scelfo, V Barra, N Abdennur, G Spracklin, F Busato… - bioRxiv, 2023 - biorxiv.org
ABSTRACT DNA methylation (DNAme) is a key epigenetic mark that regulates critical
biological processes maintaining overall genome stability. Given its pleiotropic function …

Epigenetic modifications of gonadotropin receptors can regulate follicular development

Y Yang, W Feng, J Zhou, R Zhang, X Lin… - Animal Reproduction …, 2024 - Elsevier
The spatiotemporal transcription of follicle-stimulating hormone receptor (FSHR) and
luteinizing hormone/human chorionic gonadotropin receptor (LHCGR) are crucial events for …

Sexual dimorphism of DNA and histone methylation profiles in the gonads of the olive flounder Paralichthys olivaceus

Y Liu, W Wang, S Liang, L Wang, Y Zou, Z Wu… - Fish Physiology and …, 2021 - Springer
DNA methylation and histone methylation are two types of the most important epigenetic
modifications. However, research on their differential expression in gonads of male and …

The Association Between Breast Cancer and Blood-Based Methylation of CD160, ISYNA1 and RAD51B in the Chinese Population

C Liu, X Zhou, J Jin, Q Zhu, L Li, Q Yin, T Xu… - Frontiers in …, 2022 - frontiersin.org
Recent studies have identified DNA methylation signatures in the white blood cells as
potential biomarkers for breast cancer (BC) in the European population. Here, we …

Fetal membrane epigenetics

T Zakar, JW Paul - Frontiers in Physiology, 2020 - frontiersin.org
The characteristics of fetal membrane cells and their phenotypic adaptations to support
pregnancy or promote parturition are defined by global patterns of gene expression …

Dynamics in the expression of epigenetic modifiers and histone modifications in perinatal rat germ cells during de novo DNA methylation

A Rwigemera, R El omri-Charai… - Biology of …, 2021 - academic.oup.com
Epigenetic reprogramming during perinatal germ cell development is essential for genomic
imprinting and cell differentiation; however, the actors of this key event and their dynamics …

Quantitative determination of histone methylation via fluorescence resonance energy transfer (FRET) technology in immortalized bovine mammary alveolar epithelial …

F Rosa, JS Osorio - Plos one, 2020 - journals.plos.org
Methionine (Met) is an essential precursor of S-adenosylmethionine (SAM), which is the
primary methyl donor required for biological processes such as DNA and histone …

OPEN ACCESS EDITED BY

M Sanyal, K Tabynov, B Schepens… - Methods in Vaccines …, 2024 - books.google.com
Methods: In current work we developed a recombinant adeno-associated viral vector (rAAV),
expressing a SARS-CoV-2 spike receptor-binding domain (RBD)-specific antibody P2C5 …

Molecular mechanisms of cognitive impairment in a maternal immune activation model for schizophrenia in the rat

RM Woods - 2023 - search.proquest.com
Schizophrenia is a debilitating neuropsychiatric disorder with heterogenous symptoms
across three key domains: positive, negative and cognitive symptoms. Current therapeutic …