Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders

TU Maioli, E Borras-Nogues, L Torres… - Frontiers in …, 2021 - frontiersin.org
Metabolic disorders are an increasing concern in the industrialized world. Current research
has shown a direct link between the composition of the gut microbiota and the pathogenesis …

From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity

NL Trevaskis, LM Kaminskas, CJH Porter - Nature reviews Drug …, 2015 - nature.com
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Current state and challenges in developing oral vaccines

JEV Ramirez, LA Sharpe, NA Peppas - Advanced drug delivery reviews, 2017 - Elsevier
While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …

Mechanisms of immune regulation in allergic diseases: the role of regulatory T and B cells

O Palomares, M Akdis, M Martín‐Fontecha… - Immunological …, 2017 - Wiley Online Library
Allergy is a major public health problem with a high socio‐economic impact. The number of
allergic patients is expected to reach to four billion within two decades when the World's …

[HTML][HTML] Regulation of lung immunity and host defense by the intestinal microbiota

DR Samuelson, DA Welsh, JE Shellito - Frontiers in microbiology, 2015 - frontiersin.org
Every year in the United States approximately 200,000 people die from pulmonary
infections, such as influenza and pneumonia, or from lung disease that is exacerbated by …

The PD‐1 pathway in tolerance and autoimmunity

LM Francisco, PT Sage, AH Sharpe - Immunological reviews, 2010 - Wiley Online Library
Regulatory T cells (Tregs) and the PD‐1: PD‐ligand (PD‐L) pathway are both critical to
terminating immune responses. Elimination of either can result in the breakdown of …

IL‐6: regulator of Treg/Th17 balance

A Kimura, T Kishimoto - European journal of immunology, 2010 - Wiley Online Library
IL‐6 is a pleiotropic cytokine involved in the physiology of virtually every organ system.
Recent studies have demonstrated that IL‐6 has a very important role in regulating the …

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

JM Weiss, AM Bilate, M Gobert, Y Ding… - Journal of Experimental …, 2012 - rupress.org
Foxp3 activity is essential for the normal function of the immune system. Two types of
regulatory T (T reg) cells express Foxp3, thymus-generated natural T reg (nT reg) cells, and …

[PDF][PDF] Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria

U Hadis, B Wahl, O Schulz, M Hardtke-Wolenski… - Immunity, 2011 - cell.com
Tolerance to food antigen manifests in the absence and/or suppression of antigen-specific
immune responses locally in the gut but also systemically, a phenomenon known as oral …

[PDF][PDF] World Allergy Organization (WAO) diagnosis and rationale for action against cow's milk allergy (DRACMA) guidelines

A Fiocchi, J Brozek… - World Allergy …, 2010 - waojournal.biomedcentral.com
Alessandro Fiocchi,(Chair), Jan Brozek, Holger Schünemann,(Chair), Sami L. Bahna,
Andrea von Berg, Kirsten Beyer, Martin Bozzola, Julia Bradsher, Enrico Compalati, Motohiro …