COVID-19 has emerged as a global pandemic. It is mainly manifested as pneumonia which
may deteriorate into severe respiratory failure. The major hallmark of the disease is the …

Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

There is an urgent need to identify which COVID-19 patients will develop life-threatening
illness so that medical resources can be optimally allocated and rapid treatment can be …

Abstract Background So far, SARS-CoV-2 is the seventh coronavirus found to infect humans
and cause disease with quite a strong infectivity. Patients diagnosed as severe or critical …

Abstract Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and cancer. High …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is capable of inducing the
activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) …

Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

COVID-19 can cause fever, cough, headache, and shortness of breath but patients with
comorbidities can experience worsening and death. An action is needed to treat this …

Background Increasing evidence suggests that secondary sclerosing cholangitis (SSC),
which can lead to cirrhosis or liver failure, may be a hepatobiliary long-term complication of …