Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural
Network for the challenging task of brain lesion segmentation. The devised architecture is …

Comorbidities are a hallmark of stroke that both increase the incidence of stroke and worsen
outcome. Hypertension is prevalent in the stroke population and the most important …

Thanks to its safety and accessibility, magnetic resonance imaging (MRI) is extensively used
in clinical routine and research field, largely contributing to our understanding of the …

Post-stroke cognitive impairment occurs frequently in the patients with stroke. The
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …

The term cerebral small vessel disease refers to a group of pathological processes with
various aetiologies that affect the small arteries, arterioles, venules, and capillaries of the …

Objectives To review the evidence for an association of white matter hyperintensities with
risk of stroke, cognitive decline, dementia, and death. Design Systematic review and meta …

Healthy cognitive ageing is a societal and public health priority. Cerebrovascular risk factors
increase the likelihood of dementia in older people but their impact on cognitive ageing in …

With increasing knowledge of clinical in vivo biomarkers and the pathological intricacies of
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …