[HTML][HTML] New pathological and clinical insights in endometrial cancer in view of the updated ESGO/ESTRO/ESP guidelines

A Santoro, G Angelico, A Travaglino, F Inzani… - Cancers, 2021 - mdpi.com
Simple Summary Histopathological classification of endometrial carcinoma has evidenced
two main groups with different biological behavior: low-grade (G1–G2) and high-grade (G3) …

Key changes to the World Health Organization (WHO) classification of female genital tumours introduced in the 5th edition (2020)

WG McCluggage, N Singh, CB Gilks - Histopathology, 2022 - Wiley Online Library
An updated World Health Organization (WHO) classification of female genital tumours was
published in autumn 2020. We discuss the major new additions to and changes from the …

[HTML][HTML] Dostarlimab for primary advanced or recurrent endometrial cancer

MR Mirza, DM Chase, BM Slomovitz… - … England Journal of …, 2023 - Mass Medical Soc
Background Dostarlimab is an immune-checkpoint inhibitor that targets the programmed cell
death 1 receptor. The combination of chemotherapy and immunotherapy may have …

[HTML][HTML] Lenvatinib plus pembrolizumab for advanced endometrial cancer

V Makker, N Colombo, A Casado Herráez… - … England Journal of …, 2022 - Mass Medical Soc
Background Standard therapy for advanced endometrial cancer after failure of platinum-
based chemotherapy remains unclear. Methods In this phase 3 trial, we randomly assigned …

FIGO staging of endometrial cancer: 2023

JS Berek, X Matias‐Guiu, C Creutzberg… - … of Gynecology & …, 2023 - Wiley Online Library
Introduction Many advances in the understanding of the pathologic and molecular features
of endometrial cancer have occurred since the FIGO staging was last updated in 2009 …

Cancer of the corpus uteri: 2021 update

M Koskas, F Amant, MR Mirza… - International Journal of …, 2021 - Wiley Online Library
Endometrial cancer is the most common gynecological malignancy in high‐and middle‐
income countries. Although the overall prognosis is relatively good, high‐grade endometrial …

[HTML][HTML] Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry

L Vermij, JJ Jobsen, A León-Castillo… - British journal of …, 2023 - nature.com
Background Risk-assessment of endometrial cancer (EC) is based on clinicopathological
factors and molecular subgroup. It is unclear whether adding hormone receptor expression …

[HTML][HTML] Novel insights into molecular mechanisms of endometrial diseases

T Golia D'Augè, I Cuccu, G Santangelo, L Muzii… - Biomolecules, 2023 - mdpi.com
Endometrial diseases are the most common gynecological pathologies in Western
Countries. Among these, endometrial cancer (EC) is the most common gynecological …

Endometrial cancer

EJ Crosbie, SJ Kitson, JN McAlpine, A Mukhopadhyay… - The Lancet, 2022 - thelancet.com
Endometrial cancer is the most common gynaecological cancer in high income countries
and its incidence is rising globally. Although an ageing population and fewer benign …

[HTML][HTML] Role of genomic and molecular biology in the modulation of the treatment of endometrial cancer: narrative review and perspectives

I Cuccu, O D'Oria, L Sgamba, E De Angelis… - Healthcare, 2023 - mdpi.com
Endometrial cancer (EC) is one of the most common gynecological malignancies in Western
countries. Traditionally, loco-reginal dissemination and histological characteristics are the …