ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and
renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive …

Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Background Electrocardiographic markers of left ventricular hypertrophy (LVH) predict poor
prognosis. We determined whether the ACE inhibitor ramipril prevents the development and …

▪ Abstract This review discusses the rapidly progressing field of cardiomyocyte signal
transduction and the regulation of the hypertrophic response. When stimulated by a wide …

This is a metaanalysis of all available studies as of December 1990 that have evaluated the
effect of antihypertensive pharmacologic therapy on left ventricular structure examined by …

A ngiotensin-converting enzyme (ACE) inhibitors are commonly used drugs in the
management of a variety of cardiovascular diseases. They are effective antihypertensive …

We compared the activity and physiologic effects of cardiac angiotensin converting enzyme
(ACE) using isovolumic hearts from male Wistar rats with left ventricular hypertrophy due to …

Renin was first isolated in the kidney by Tigerstedt and Bergman over 100 years ago. Almost
50 additional years were necessary to isolate the renin substrate angiotensinogen and to …

Synopsis: Enalapril maleate 1 is an orally active angiotensin-converting enzyme inhibitor. It
lowers peripheral vascular resistance without causing an increase in heart rate. Enalapril 10 …

Background—Many studies have suggested that the renin-angiotensin system plays an
important role in the development of pressure overload–induced cardiac hypertrophy …