[HTML][HTML] Vagus nerve stimulation: a personalized therapeutic approach for crohn's and other inflammatory bowel diseases

G Cirillo, F Negrete-Diaz, D Yucuma, A Virtuoso… - Cells, 2022 - mdpi.com
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are incurable
autoimmune diseases characterized by chronic inflammation of the gastrointestinal tract …

Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management

ZH McMahan, S Kulkarni, J Chen, JZ Chen… - Nature Reviews …, 2023 - nature.com
Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the
gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high …

[HTML][HTML] Effect of tea polyphenols on the prevention of neurodegenerative diseases through gut microbiota

L Xu, R Wang, Y Liu, S Zhan, Z Wu, X Zhang - Journal of Functional Foods, 2023 - Elsevier
Tea polyphenols (TPs) have shown several memory-enhancing activities. The gut
microbiota is essential in developing neurodegenerative diseases as a critical regulator of …

Molecular cell types as functional units of the efferent vagus nerve

TC Coverdell, SBG Abbott, JN Campbell - Seminars in Cell & …, 2023 - Elsevier
The vagus nerve vitally connects the brain and body to coordinate digestive,
cardiorespiratory, and immune functions. Its efferent neurons, which project their axons from …

The enteric nervous system

KA Sharkey, GM Mawe - Physiological reviews, 2023 - journals.physiology.org
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …

[HTML][HTML] Disengaging spinal afferent nerve communication with the brain in live mice

MA Kyloh, TJ Hibberd, J Castro, AM Harrington… - Communications …, 2022 - nature.com
Our understanding of how abdominal organs (like the gut) communicate with the brain, via
sensory nerves, has been limited by a lack of techniques to selectively activate or inhibit …

[HTML][HTML] Neuroimmunophysiology of the gastrointestinal tract

DM McKay, M Defaye, S Rajeev… - American Journal …, 2024 - journals.physiology.org
Gut physiology is the epicenter of a web of internal communication systems (ie, neural,
immune, hormonal) mediated by cell-cell contacts, soluble factors, and external influences …

[HTML][HTML] Neuromodulation and the Gut–Brain Axis: Therapeutic Mechanisms and Implications for Gastrointestinal and Neurological Disorders

B Aljeradat, D Kumar, S Abdulmuizz, M Kundu… - Pathophysiology, 2024 - mdpi.com
The gut–brain axis (GBA) represents a complex, bidirectional communication network that
intricately connects the gastrointestinal tract with the central nervous system (CNS) …

Coexpressed δ-, μ-, and κ-Opioid Receptors Modulate Voltage-Gated Ca2+ Channels in Gastric-Projecting Vagal Afferent Neurons

HJ Goudsward, V Ruiz-Velasco, SL Stella… - Molecular …, 2024 - ASPET
Opioid analgesics are frequently associated with gastrointestinal side effects, including
constipation, nausea, dysphagia, and reduced gastric motility. Though it has been shown …

[HTML][HTML] The vagus nerve mediates the stomach-brain coherence in rats

J Cao, X Wang, J Chen, N Zhang, Z Liu - NeuroImage, 2022 - Elsevier
Interactions between the brain and the stomach shape both cognitive and digestive
functions. Recent human studies report spontaneous synchronization between brain activity …