The occurrence and development of tumors is a multi-factor, multi-step, multi-gene
pathological process, and its treatment has been the most difficult problem in the field of …

Many factors are involved in the development of cancer pain, which is a serious
complication of cancer and affects the quality of life of patients, Normally, drugs are used to …

Cholestasis is a severe clinical complication that severely damages the liver. Kidneys are
also the most affected extrahepatic organs in cholestasis. The pivotal role of oxidative stress …

Several studies have focused on the high potential effects of probiotics on the reproductive
system. However, there is a paucity of information regarding the ameliorative intracellular …

The most common joint disease in the elderly is knee osteoarthritis (OA). It is distinguished
by cartilage degradation, subchondral bone loss, and a decrease in joint space. We studied …

Although intervertebral disc degeneration (IDD) can be described as different stages of
change through biological methods, this long and complex process cannot be defined in …

Lithium (Li+) is prescribed against a wide range of neurological disorders. Besides its
excellent therapeutic properties, there are several adverse effects associated with Li+. The …

Lead (Pb) is a highly toxic heavy metal. Pb exposure could adversely affect many organs,
including the male reproductive system. Oxidative stress and mitochondrial impairment play …

Cirrhosis-induced heart injury and cardiomyopathy is a serious consequence of this
disease. It has been shown that bile duct ligated (BDL) animals could serve as an …

Results Severe elevation in serum and urine biomarkers of renal injury was evident in the
BDL group. Significant lipid peroxidation, reactive oxygen species (ROS) formation, and …