The pharmaceutical industry is under growing pressure from a range of environmental
issues, including major losses of revenue owing to patent expirations, increasingly cost …

Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …

Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

We propose a novel recursive partitioning method for identifying subgroups of subjects with
enhanced treatment effects based on a differential effect search algorithm. The idea is to …

Simple Summary The progress of next-generation sequencing technologies has raised
huge expectations for precision-medicine therapy approaches in breast cancer and triple …

The objective of this article was to provide a framework for understanding the different
definitions of the term “personalized medicine.” The term personalized medicine is used …

Societal expectations about drug safety and efficacy are rising while productivity in the
pharmaceutical industry is falling. In 2004, the US Food and Drug Administration introduced …

Study Objectives. To review the labels of United States Food and Drug Administration (FDA)‐
approved drugs to identify those that contain pharmacogenomic biomarker information, and …

Interest in pharmaceuticals in the environment has increased substantially in recent years.
Several studies in particular have assessed human and ecological risks from human …

In June 2012, 13 thought leaders convened in a Diabetes Care Editors' Expert Forum to
discuss the concept of personalized medicine in the wake of a recently published American …