Objective Polypharmacy is widespread among older people, but the adverse outcomes
associated with it are unclear. We aim to synthesize current evidence on the adverse health …

Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …

Abstract Background General practitioners (GPs) increasingly manage patients with
multimorbidity but report challenges in doing so. Patients describe poor experiences with …

Background Harmful and/or unnecessary medication use in older adults is common. This
indicates deprescribing (supervised withdrawal of inappropriate medicines) is not …

Background Managing polypharmacy is a challenge for healthcare systems globally. It is
also a health inequality concern as it can expose some of the most vulnerable in society to …

Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …

Objectives Polypharmacy in the older population is increasing—and can be harmful. It can
be safe to reduce or carefully cease medicines (deprescribing) but a collaborative approach …

Background Prolonged use of anticholinergic and sedative medicines is correlated with
worsening cognition and physical function decline. Deprescribing is a proposed intervention …

Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

What is known and objective Deprescribing is the process of discontinuing or reducing the
dosage of medications that are no longer appropriate or aligned with goals of care, which is …