[HTML][HTML] High dietary fructose: direct or indirect dangerous factors disturbing tissue and organ functions

DM Zhang, RQ Jiao, LD Kong - Nutrients, 2017 - mdpi.com
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome,
disturbing tissue and organ functions. Fructose is mainly absorbed into systemic circulation …

[HTML][HTML] Dietary sugars and endogenous formation of advanced glycation endproducts: emerging mechanisms of disease

M Aragno, R Mastrocola - Nutrients, 2017 - mdpi.com
The rapid increase in metabolic diseases, which occurred in the last three decades in both
industrialized and developing countries, has been related to the rise in sugar-added foods …

[HTML][HTML] Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice

E Benetti, R Mastrocola, F Chiazza, D Nigro… - PloS one, 2018 - journals.plos.org
Epidemiological studies pointed out to a strong association between vitamin D deficiency
and type 2 diabetes prevalence. However, the role of vitamin D supplementation in the …

[HTML][HTML] High-intensity interval training restores glycolipid metabolism and mitochondrial function in skeletal muscle of mice with type 2 diabetes

L Zheng, Z Rao, Y Guo, P Chen, W Xiao - Frontiers in Endocrinology, 2020 - frontiersin.org
High-intensity interval training has been reported to lower fasting blood glucose and
improve insulin resistance of type 2 diabetes without clear underlying mechanisms. The …

Mechanisms of autophagic responses to altered nutritional status

Z Tao, H Aslam, J Parke, M Sanchez… - The Journal of Nutritional …, 2022 - Elsevier
Autophagy is a dynamic process and critical for cellular remodeling and organelle quality
control. In response to altered nutritional status (eg, fasting and feeding), autophagic activity …

[HTML][HTML] Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring

Y Huang, S Gao, J Chen, E Albrecht, R Zhao, X Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Maternal nutrition is important for the risk of the offspring to develop insulin resistance and
adiposity later in life. The study was undertaken to determine effects of maternal butyrate …

Skeletal muscle insulin resistance and adipose tissue hypertrophy persist beyond the reshaping of gut microbiota in young rats fed a fructose-rich diet

A Mazzoli, A Di Porzio, C Gatto, R Crescenzo… - The Journal of …, 2023 - Elsevier
To investigate whether short term fructose-rich diet induces changes in the gut microbiota as
well as in skeletal muscle and adipose tissue physiology and verify whether they persist …

Long-term treatment with nicotinamide induces glucose intolerance and skeletal muscle lipotoxicity in normal chow-fed mice: compared to diet-induced obesity

Z Qi, J Xia, X Xue, Q He, L Ji, S Ding - The Journal of nutritional …, 2016 - Elsevier
Nicotinamide (NAM), or vitamin B3, is an essential coenzyme for ATP synthesis and an
inhibitor of sirtuin 1. Recently, conflicting results were reported regarding the treatment of …

Brain Nrf2 pathway, autophagy, and synaptic function proteins are modulated by a short-term fructose feeding in young and adult rats

MS Spagnuolo, P Bergamo, R Crescenzo… - Nutritional …, 2020 - Taylor & Francis
Objectives: A strong rise of the fructose content in the human diet occurred in the last
decade, as corn syrup is widely used as a sweetener for beverages and processed food …

[HTML][HTML] The frequency of daily consumption of sugar-sweetened beverages is associated with reduced muscle mass index in adolescents

MLBM Bragança, CCNS Coelho, BR Oliveira… - Nutrients, 2022 - mdpi.com
The consumption of sugar-sweetened beverages (SSBs) has increased in recent years and
has become a cause of concern because these beverages pose a risk to human health …