Circulating oxidative stress biomarkers in clinical studies on type 2 diabetes and its complications

E Bigagli, M Lodovici - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Type 2 diabetes (T2DM) and its complications constitute a major worldwide public health
problem, with high rates of morbidity and mortality. Biomarkers for predicting the occurrence …

Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic …

Y Shokri, A Variji, M Nosrati, A Khonakdar-Tarsi… - Diabetes research and …, 2020 - Elsevier
Oxidant–antioxidant imbalance is involved in the etiology of different diseases, including
cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes …

Paraoxonase 1 and atherosclerosis‐related diseases

J Kotur‐Stevuljević, J Vekić, A Stefanović… - Biofactors, 2020 - Wiley Online Library
A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …

Connection between the Altered HDL Antioxidant and Anti‐Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review

F Zimetti, MP Adorni, J Marsillach… - Oxidative medicine …, 2021 - Wiley Online Library
The protein composition of high‐density lipoprotein (HDL) is extremely fluid. The quantity
and quality of protein constituents drive the multiple biological functions of these …

Shared metabolic and neuroimmune mechanisms underlying type 2 diabetes mellitus and major depressive disorder

E Duarte-Silva, MG de Melo, M Maes… - Progress in Neuro …, 2021 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease with symptoms that
go beyond the domain of glucose metabolism. In fact, research has shown that T2DM is …

The Beneficial Effects of Alpha Lipoic Acid Supplementation on Lp‐PLA2 Mass and Its Distribution between HDL and apoB‐Containing Lipoproteins in Type 2 …

N Baziar, E Nasli-Esfahani, K Djafarian… - Oxidative medicine …, 2020 - Wiley Online Library
Lipoprotein‐associated phospholipase A2 (Lp‐PLA2) is a new specific vascular
inflammation biomarker that is carried by the lipoproteins in the blood and plays a prominent …

Crosstalk between adipokines and paraoxonase 1: a new potential axis linking oxidative stress and inflammation

V Tisato, A Romani, E Tavanti, E Melloni, D Milani… - Antioxidants, 2019 - mdpi.com
Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated protein that endows
its carrier with (lipo-) lactonase-dependent antioxidative features. Low levels of PON1 …

Lipoprotein-associated phospholipase A2 activity as potential biomarker of vascular dementia

G Zuliani, J Marsillach, A Trentini, V Rosta, C Cervellati - Antioxidants, 2023 - mdpi.com
A wealth of evidence suggests that Lipoprotein-associated phospholipase A2 (Lp-PLA2)
plays a relevant role in atherogenesis and inflammation, which in turn are associated with …

High-density lipoprotein cholesterol efflux capacity and cardiovascular risk in autoimmune and non-autoimmune diseases

A Hafiane, E Favari, SS Daskalopoulou, N Vuilleumier… - Metabolism, 2020 - Elsevier
Functional assessment of cholesterol efflux capacity (CEC) to high-density lipoprotein (HDL)
is an emerging tool for evaluating morbidity and mortality associated with cardiovascular …

Paraoxonase 1 activity, polymorphism and atherosclerosis risk factors in patients undergoing coronary artery surgery

A Wysocka, M Cybulski, AP Wysokiński… - Journal of Clinical …, 2019 - mdpi.com
Background: Paraoxonase1 (PON1), an enzyme connected to high density lipoproteins
(HDL) particles, plays an important role in protecting arteries against atherosclerosis. The …