Macrophages in necrotic liver lesion repair: opportunities for therapeutical applications
Y Wang, RM Rodrigues, C Chen… - … of Physiology-Cell …, 2024 - journals.physiology.org
Healthy livers contain 80% of body resident macrophages known as Kupffer cells. In
diseased livers, the number of Kupffer cells usually drops but is compensated by infiltration …
diseased livers, the number of Kupffer cells usually drops but is compensated by infiltration …
Alcohol-associated liver cancer
Heavy alcohol intake induces a wide spectrum of liver diseases ranging from steatosis,
steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Although alcohol …
steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Although alcohol …
Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption
Y Fu, B Mackowiak, YH Lin, L Maccioni, T Lehner… - Nature …, 2024 - nature.com
Alcohol use disorder (AUD) affects millions of people worldwide, causing extensive
morbidity and mortality with limited pharmacological treatments. The liver is considered as …
morbidity and mortality with limited pharmacological treatments. The liver is considered as …
Platelets in Alcohol-associated Liver Disease-Interaction with Neutrophils
J Wang, X Wang, H Peng, Z Dong… - Cellular and Molecular …, 2024 - Elsevier
Alcohol-associated liver disease (ALD) is a major contributor to liver-related mortality
globally. A growing body of evidence underscores the pivotal role of platelets throughout the …
globally. A growing body of evidence underscores the pivotal role of platelets throughout the …
[HTML][HTML] Protective effects of Abrus cantoniensis Hance against liver injury through modulation of intestinal microbiota and liver metabolites
C Xu, M Ali, J Sun, X Li, D Fouad, M Iqbal… - Ecotoxicology and …, 2024 - Elsevier
Abrus cantoniensis Hance (ACH) is an ancient Chinese medicine herb known for its
therapeutic effects. This study investigated the potential protective effect of ACH against …
therapeutic effects. This study investigated the potential protective effect of ACH against …
Necrotic Liver Lesion Resolution: Another Mode of Liver Regeneration
The liver has the great ability to regenerate after partial resection or injury, and the
mechanisms underlying liver regeneration have been extensively investigated. Interestingly …
mechanisms underlying liver regeneration have been extensively investigated. Interestingly …
Inflammation in Steatotic Liver Diseases: Pathogenesis and Therapeutic Targets
S Qian, X Wang, Y Chen, Q Zai… - Seminars in Liver …, 2024 - thieme-connect.com
Alcohol-related liver disease (ALD) and metabolic dysfunction-associated steatotic liver
disease (MASLD), two main types of steatotic liver disease (SLDs), are characterized by a …
disease (MASLD), two main types of steatotic liver disease (SLDs), are characterized by a …
Liver injury protection of Artemisia stechmanniana Besser through PI3K/AKT pathway
CB Tian, ML Qin, YL Qian, SS Qin, ZQ Shi… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Artemisia stechmanniana Besser, one of the most
prevalent botanical medicines in Chinese, has been traditionally used for hepatitis …
prevalent botanical medicines in Chinese, has been traditionally used for hepatitis …
Shaping new paths in clinical trial design to address alcohol use disorders and alcohol-associated liver disease
J Serrazina, H Cortez-Pinto - Nature Reviews Gastroenterology & …, 2024 - nature.com
An expert panel has proposed 28 recommendations for the design and conduct of clinical
trials for alcohol use disorders and alcohol-associated liver disease. This field has a scarcity …
trials for alcohol use disorders and alcohol-associated liver disease. This field has a scarcity …
Heterogeneity in Liver Cancer Immune Microenvironment: Emerging Single-Cell and Spatial Perspectives
Primary liver cancer is a solid malignancy with a high mortality rate. The success of
immunotherapy has shown great promise in improving patient care and highlights a crucial …
immunotherapy has shown great promise in improving patient care and highlights a crucial …