Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

Bacterial conjugation is one of the main mechanisms for horizontal gene transfer. It
constitutes a key element in the dissemination of antibiotic resistance and virulence genes to …

Conjugation is the process by which bacteria exchange genetic materials in a unidirectional
manner from a donor cell to a recipient cell. The discovery of conjugation signalled the dawn …

Bacterial conjugation in Gram-negative bacteria is triggered by a signal that connects the
relaxosome to the coupling protein (T4CP) and transferosome, a type IV secretion system …

The F plasmid or F-factor is a large, 100-kbp, circular conjugative plasmid of Escherichia coli
and was originally described as a vector for horizontal gene transfer and gene …

Meiosis is essential for eukaryotic sexual reproduction, with two consecutive rounds of
nuclear divisions, allowing production of haploid gametes. Information regarding the meiotic …

Relaxases play essential roles in conjugation, the main process by which bacteria exchange
genetic material, notably antibiotic resistance genes. They are bifunctional enzymes …

The tra operon of the prototypical F plasmid and its relatives enables transfer of a copy of the
plasmid to other bacterial cells via the process of conjugation. Tra proteins assemble to form …

Many soil-, water-, and plant-associated bacterial species from the orders
Xanthomonadales, Burkholderales, and Neisseriales carry a type IV secretion system …

Efficient in silico development of novel antibiotics requires high-resolution, dynamic models
of drug targets. As conjugation is considered the prominent contributor to the spread of …