[HTML][HTML] The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections

J Machhi, J Herskovitz, AM Senan, D Dutta… - Journal of neuroimmune …, 2020 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (COVID-19). SARS-CoV-2, is a positive-sense single-stranded …

Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose

C Doyno, DM Sobieraj, WL Baker - Clinical Toxicology, 2021 - Taylor & Francis
Introduction While chloroquine, a derivative of quinine, has been used as an antimalarial for
70 years, hydroxychloroquine is now used to treat conditions such as rheumatoid arthritis …

Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia

CY Chen, FL Wang, CC Lin - Clinical Toxicology, 2006 - Taylor & Francis
Background. Hydroxychloroquine (HCQ) is used for treatment of lupus erythematosus. The
cardiac toxicity of HCQ has focused primarily on acute intoxication. We report a case of …

Acute chloroquine and hydroxychloroquine toxicity: a review for emergency clinicians

A Della Porta, K Bornstein, A Coye, T Montrief… - The American journal of …, 2020 - Elsevier
Background Acute chloroquine and hydroxychloroquine toxicity is characterized by a
combination of direct cardiovascular effects and electrolyte derangements with resultant …

[HTML][HTML] Chloroquine and hydroxychloroquine toxicity

TJ Stokkermans, DM Falkowitz, G Trichonas - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Objectives: Identify the treatment indications for chloroquine and hydroxychloroquine.
Determine the mechanisms of action of chloroquine and hydroxychloroquine. Identify the …

Hydroxychloroquine cardiotoxicity in systemic lupus erythematosus: a report of 2 cases and review of the literature

JE Nord, PK Shah, RZ Rinaldi, MH Weisman - Seminars in arthritis and …, 2004 - Elsevier
BACKGROUND: Hydroxychloroquine (HCQ) is extensively used in the long-term treatment
of systemic lupus erythematosus (SLE). Although considered by clinicians to be relatively …

[HTML][HTML] Hydroxychloroquine in COVID-19 patients: pros and cons

NK Younis, RO Zareef, SN Al Hassan, F Bitar… - Frontiers in …, 2020 - frontiersin.org
The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical
centers and paralyzed economies. The unparalleled public distress caused by this …

Effect of hydroxychloroquine and azithromycin on QT interval prolongation and other cardiac arrhythmias in COVID‐19 confirmed patients

SP Eftekhar, S Kazemi, M Barary… - Cardiovascular …, 2021 - Wiley Online Library
Background. Hydroxychloroquine with or without azithromycin was one of the common
therapies at the beginning of the COVID‐19 pandemic. They can prolong QT interval, cause …

Ultrasonic-Assisted Fabrication of MIL-100 (Fe) Metal–Organic Frameworks as a Carrier for the Controlled Delivery of the Chloroquine Drug

BT Le, DD La, PTH Nguyen - ACS omega, 2022 - ACS Publications
Metal–organic framework materials (MOFs) are materials with an ordered crystalline
structure and high porosity that have been intensively investigated for many applications …

Repurposing drugs for COVID-19: Pharmacokinetics and pharmacogenomics of chloroquine and hydroxychloroquine

M Babayeva, Z Loewy - Pharmacogenomics and personalized …, 2020 - Taylor & Francis
Background A new coronavirus SARS-CoV-2 has been identified as the etiological agent of
the severe acute respiratory syndrome, COVID-19, the source and cause of the 2019–20 …