[HTML][HTML] Fetal alcohol spectrum disorders

S Popova, ME Charness, L Burd, A Crawford… - Nature reviews Disease …, 2023 - nature.com
Alcohol readily crosses the placenta and may disrupt fetal development. Harm from prenatal
alcohol exposure (PAE) is determined by the dose, pattern, timing and duration of exposure …

Ethanol and its metabolites: update on toxicity, benefits, and focus on immunomodulatory effects

B Le Dare, V Lagente, T Gicquel - Drug metabolism reviews, 2019 - Taylor & Francis
This article summarizes recent experimental and epidemiological data on the toxic and
beneficial effects of ethanol and its metabolites (acetaldehyde), and focuses on their …

[HTML][HTML] Single-cell epigenomics reveals mechanisms of human cortical development

RS Ziffra, CN Kim, JM Ross, A Wilfert, TN Turner… - Nature, 2021 - nature.com
During mammalian development, differences in chromatin state coincide with cellular
differentiation and reflect changes in the gene regulatory landscape. In the developing brain …

Environmental risk factors for congenital heart disease

JI Kalisch-Smith, N Ved… - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) has many forms and a wide range of causes. Clinically, it is
important to understand the causes. This allows estimation of recurrence rate, guides …

Environmental mechanisms of orofacial clefts

MA Garland, K Reynolds, CJ Zhou - Birth defects research, 2020 - Wiley Online Library
Orofacial clefts (OFCs) are among the most common birth defects and impart a significant
burden on afflicted individuals and their families. It is increasingly understood that many …

[HTML][HTML] Alcohol and breast cancer

B Starek-Świechowicz, B Budziszewska… - Pharmacological …, 2023 - Springer
Breast cancer is one of the main causes of death in women worldwide. In women, breast
cancer includes over half of all tumours caused by alcohol. This paper discusses both …

[HTML][HTML] Alcohol in Psoriasis—from bench to bedside

Z Szentkereszty-Kovács, K Gáspár, A Szegedi… - International journal of …, 2021 - mdpi.com
Alcohol affects the symptoms, compliance and comorbidities as well as the safety and
efficacy of treatments in psoriatic patients. In this review, we aim to summarize and link …

[HTML][HTML] Analyses of commercially available alcohol-based hand rubs formulated with compliant and non-compliant ethanol

TJ Tse, FB Nelson, MJT Reaney - International journal of environmental …, 2021 - mdpi.com
The COVID-19 pandemic led to panic-buying of alcohol-based hand rubs (ABHRs). In
response, governmental agencies (eg, Health Canada) permitted the sale of ABHRs …

Insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorder

B Petrelli, L Bendelac, GG Hicks, A Fainsod - Genesis, 2019 - Wiley Online Library
Summary Fetal Alcohol Spectrum Disorder (FASD) is a set of neurodevelopmental
malformations caused by maternal consumption of alcohol during pregnancy. FASD sentinel …

[HTML][HTML] Toxicology of alcohol-based hand rubs formulated with technical-grade ethanol

JT Timothy, SK Purdy, J Shen, FB Nelson, R Mustafa… - Toxicology Reports, 2021 - Elsevier
Alcohol-based hand rubs (ABHRs) formulated with technical-grade ethanol were temporarily
permitted in Canada and the US beginning April 2020 to meet the current demand due to …