Metal-hydride hydrogen atom transfer (MHAT) reactions in natural product synthesis

J Wu, Z Ma - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The metal-hydride hydrogen atom transfer (MHAT) reaction plays an important role in the
field of natural product synthesis. MHAT, as a powerful method, has been employed by …

[HTML][HTML] Mitsunobu reaction: a powerful tool for the synthesis of natural products: a review

S Munawar, AF Zahoor, S Ali, S Javed, M Irfan, A Irfan… - Molecules, 2022 - mdpi.com
The Mitsunobu reaction plays a vital part in organic chemistry due to its wide synthetic
applications. It is considered as a significant reaction for the interconversion of one …

[HTML][HTML] Promising technological and industrial applications of deep eutectic systems

A Mannu, M Blangetti, S Baldino, C Prandi - Materials, 2021 - mdpi.com
Deep Eutectic Systems (DESs) are obtained by combining Hydrogen Bond Acceptors
(HBAs) and Hydrogen Bond Donors (HBDs) in specific molar ratios. Since their first …

Alcohols as Substrates in Transition-Metal-Catalyzed Arylation, Alkylation, and Related Reactions

A Cook, SG Newman - Chemical Reviews, 2024 - ACS Publications
Alcohols are abundant and attractive feedstock molecules for organic synthesis. Many
methods for their functionalization require them to first be converted into a more activated …

[HTML][HTML] Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases

T Gou, M Hu, M Xu, Y Chen, R Chen, T Zhou… - Journal of …, 2023 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) frequently results in sudden death and
poses a serious threat to public health worldwide. The drugs approved for the prevention …

[HTML][HTML] A New Source of Diterpene Lactones From Andrographis paniculata (Burm. f.) Nees—Two Endophytic Fungi of Colletotrichum sp. With Antibacterial and …

N Li, D Xu, RH Huang, JY Zheng, YY Liu… - Frontiers in …, 2022 - frontiersin.org
Endophytic fungi of medicinal plants are abundant, and their metabolites often have
antioxidant, antibacterial, and antitumor effects and can produce secondary metabolites …

Deep eutectic solvents as H2-sources for Ru (II)-catalyzed transfer hydrogenation of carbonyl compounds under mild conditions

M Cavallo, D Arnodo, A Mannu, M Blangetti, C Prandi… - Tetrahedron, 2021 - Elsevier
The employment of easily affordable ruthenium (II)-complexes as pre-catalysts in the transfer
hydrogenation of carbonyl compounds in deep eutectic media is described for the first time …

[HTML][HTML] Natural and synthetic lactones possessing antitumor activities

Y Kim, S Sengupta, T Sim - International Journal of Molecular Sciences, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, accounting for an estimated 8 million
deaths each year. As a result, there have been urgent unmet medical needs to discover …

DFT mechanistic study of [4+ 2] cycloaddition reactions of 1-methyl-1H-pyrrole-2, 5-dione with furoic acid, anticancer Activity, molecular modeling and ADMET …

T Boutadghart, R Ghailane - Computational and Theoretical Chemistry, 2023 - Elsevier
Abstract The [4+ 2] cycloaddition reactions of 1-methyl-1H-pyrrole-2, 5-dione, with furan-2-
carboxylic acid, 5-methylfuran-2-carboxylic acid and 5-(hydroxymethyl)-furan-2-Carboxylic …

Enantioselective Tertiary Electrophile (Hetero) Benzylation: Pd‐Catalyzed Substitution of Isoprene Monoxide with Arylacetates

MGJ Doyle, AL Gabbey, W McNutt… - Angewandte …, 2021 - Wiley Online Library
The enantioselective generation of quaternary carbon centers remains challenging but is of
growing importance for the preparation of functional molecules. Metal catalyzed allylic …