Gastric cancer remains one of the most common cancers worldwide and one of the leading
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …

Curcumin (diferuloylmethane), a derivative of turmeric is one of the most commonly used
and highly researched phytochemicals. Abundant sources provide interesting insights into …

The Wnt signaling pathway, named for its most upstream ligands, the Wnts, is involved in
various differentiation events during embryonic development and leads to tumor formation …

Studies of Wnt activation in gastric cancer have yielded conflicting results. The goals of this
study were to determine the frequency of Wnt pathway activation and β-catenin mutation in …

Dysregulation of Wnt/β-catenin pathway plays a central role in early events in colorectal
carcinogenesis. We examined the effect of quercetin, a famous anti-tumor agent, against β …

Carcinogenesis encompasses 3 closely associated stages: initiation, progression, and
promotion. Phytochemicals are nonnutritive components of plants that are currently being …

Aim: The Wnt signaling pathway plays a pivotal role in cellular developmental processes
and human carcinogenesis. The aim of this study was to investigate the effects of quercetin …

BACKGROUND Wnt‐1 and β‐catenin expression levels play an important role in several
malignancies. The authors determined the level of production of Wnt‐1 and β‐catenin in …

Introduction: The Wnt/β-catenin signaling pathway plays a pivotal role in the regulation of
cell growth, cell development and the differentiation of normal stem cells. Constitutive …

Stabilization of β-catenin by inhibition of its phosphorylation is characteristic of an activation
of the canonical Wnt/β-catenin signaling pathway and is associated with various human …