[HTML][HTML] The Role of Chitinase-3-like Protein-1 (YKL40) in the Therapy of Cancer and Other Chronic-Inflammation-Related Diseases

MC Chang, CT Chen, PF Chiang, YC Chiang - Pharmaceuticals, 2024 - mdpi.com
Chitinase-3-like protein-1 (CHI3L1), also known as YKL40, is a glycoprotein that belongs to
the chitinase protein family. It is involved in various biological functions, including cell …

[HTML][HTML] Fully human chitinase-3 like-1 monoclonal antibody inhibits tumor growth, fibrosis, angiogenesis, and immune cell remodeling in lung, pancreatic, and …

PC Su, CY Chen, MH Yu, IY Kuo, PS Yang… - Biomedicine & …, 2024 - Elsevier
Considering the limited efficacy of current therapies in lung, colorectal, and pancreatic
cancers, innovative combination treatments with diverse mechanisms of action are needed …

New insights into the role of the CHI3L2 protein in invasive ductal breast carcinoma: the CHI3L1 protein has a different role

A Rusak, E Kątnik, T Górnicki, C Schmuttermaier… - 2024 - researchsquare.com
Purpose Chitinase-like proteins have multiple biological functions that promote tumor
growth, angiogenesis and metastasis. Expression of CHI3L2, which is similar in structure to …