Tumorigenesis, diagnosis, and therapeutic potential of exosomes in liver cancer

H Wang, Z Lu, X Zhao - Journal of hematology & oncology, 2019 - Springer
Hepatocellular carcinoma (HCC, also called primary liver cancer) is one of the most fatal
cancers in the world. Due to the insidiousness of the onset of HCC and the lack of effective …

Extracellular vesicles as biomarkers in liver diseases: a clinician's point of view

S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

Exosomal non-coding RNAs: new insights into the biology of hepatocellular carcinoma

Q Zhang, H Li, Y Liu, J Li, C Wu, H Tang - Current Oncology, 2022 - mdpi.com
Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest
extracellular vesicles released by cells. They deliver different cargoes, including proteins …

Urinary Exosomal miRNAs as biomarkers of bladder Cancer and experimental verification of mechanism of miR-93-5p in bladder Cancer

H Lin, X Shi, H Li, J Hui, R Liu, Z Chen, Y Lu, W Tan - Bmc Cancer, 2021 - Springer
Background Bladder cancer (BC) is one of the most common malignancies globally. Early
diagnosis of it can significantly improve patients' survival and quality of life. Urinary …

HCC-derived exosomes: critical player and target for cancer immune escape

Q Han, H Zhao, Y Jiang, C Yin, J Zhang - Cells, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver, and currently the
second most common cause of cancer-related deaths worldwide with increasing incidence …

Exosomes and hepatocellular carcinoma: from bench to bedside

R Sasaki, T Kanda, O Yokosuka, N Kato… - International journal of …, 2019 - mdpi.com
As hepatocellular carcinoma (HCC) usually occurs in the background of cirrhosis, which is
an end-stage form of liver diseases, treatment options for advanced HCC are limited, due to …

Advances on liver cell‐derived exosomes in liver diseases

Y Jiao, P Xu, H Shi, D Chen… - Journal of cellular and …, 2021 - Wiley Online Library
Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm, which
contain several donor cell‐associated proteins as well as mRNA, miRNA, and lipids and …

Potential role of exosomes in cancer metastasis

W Tian, S Liu, B Li - BioMed research international, 2019 - Wiley Online Library
High cancer mortality is attributed to metastasis to a large extent. However, cancer
metastasis remains devoid of dynamic monitoring and early prevention in terms of current …

Exosomal microRNAs as biomarkers and therapeutic targets for hepatocellular carcinoma

A Sorop, D Constantinescu, F Cojocaru… - International Journal of …, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the second
most common cause of cancer-related death globally. This type of liver cancer is frequently …

The significance of exosomes in the development and treatment of hepatocellular carcinoma

X Li, C Li, L Zhang, M Wu, K Cao, F Jiang, D Chen… - Molecular Cancer, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most commonmalignancy. Exsome plays a
significant role in the elucidation of signal transduction pathways between hepatoma cells …