Collective cell migration plays essential roles in a wide spectrum of biological processes,
such as embryogenesis, tissue regeneration, and cancer metastasis. Numerous wound …

The molecular mechanisms leading to tumor progression and acquisition of a metastatic
phenotype are highly complex and only partially understood. The spatiotemporal regulation …

Deoxynivalenol (vomitoxin, DON) is a secondary metabolite produced by Fusarium spp.
fungi and it is one of the most prevalent mycotoxins worldwide. Crop infestation results not …

Osteoclast and osteoblast are essential for proper bone development and remodeling as
well as recovery of bone fracture. In this study, we seek chemical compounds that enhance …

In our body cells move in three dimensions, embedded in an extracellular matrix that varies
in composition, density and stiffness, and this movement is fundamental to life. Next to 3D …

Background Renal tubular epithelial cells of proximal and distal origin differ markedly in their
physiological functions. Therefore, we hypothesized that they also differ in their capacity to …

Satellite cell migration is critical for skeletal muscle growth and regeneration. Controlled cell
migration is dependent on the formation of mature focal adhesions between the cell and the …

Background Recent clinical trials using c-kit+ human cardiac stem cells (CSCs)
demonstrated promising results in increasing cardiac function and improving quality of life …

Background: Hydra propagates asexually by exporting tissue into a bud, which detaches 4
days later as a fully differentiated young polyp. Prerequisite for detachment is activation of …

The ability of transforming growth factor β (TGFβ) to induce epithelial–mesenchymal
transition (EMT) is mediated by SMAD-dependent and SMAD-independent pathways such …