Objectives Disturbances in the myelin sheath drive disruptions in neural transmission and
brain connectivity as seen in schizophrenia. Here, the myelin proteome was characterised in …

Myelin production during brain development requires an increase in membrane protein and
lipid production in oligodendrocytes and this primarily occurs in the endoplasmic reticulum …

To obtain a thorough understanding of chronic pain, large-scale molecular mapping of the
pain axis at the protein level is necessary, but has not yet been achieved. We applied …

The process of myelination in the nervous system requires a coordinated formation of both
transient and stable supramolecular complexes. Myelin-specific proteins play key roles in …

Post-translational modifications (PTMs) play a key role in regulating protein function, yet
their identification is technically demanding. Here, we present a straightforward workflow to …

Adolescent development of prefrontal cortex (PFC) parallels maturation of executive
functions as well as increasing white matter and myelination. Studies using MRI and other …

The process of axon myelination involves various proteins including molecular chaperones.
Myelin alteration is a common feature in neurological diseases due to structural and …

Oligodendrocytes, the myelinating cells of the central nervous system, are essential for
correct brain function. They originate from oligodendrocyte precursor cells through a …

Abnormal myelin gene expression in the central nervous system (CNS) is associated with
many mental illnesses, including psychiatric disorders and drug addiction. We have …

Several different types of nonneuronal glial cells with diverse phenotypes are present in the
CNS, and all have distinct indispensible functions. Although glial cells primarily provide …