Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …

Introduction Gambogic acid (GA) is proved to have anti-tumor effects on gastric cancer. Due
to poor solubility, non-specific biological distribution, toxicity to normal tissues and short half …

Background Gastric cancer (GC) is a major cancer-related mortality disease. Gambogic acid
(GA) has been investigated to inhibit cancer progression. In the present study, the molecular …

ABSTRACT Introduction: P-glycoprotein (P-gp) is an important efflux pump responsible for
the extruding of many endogenous and exogenous substances out of the cells. P-gp can be …

Sinapic acid (Sa) is a small‐molecule phenolic acid compound predominant in fruits,
vegetables, and grains. This study investigated the antitumor effects of cisplatin (DDP) …

Photodynamic therapy (PDT) uses photosensitizer activation by light of a specific
wavelength, and is a promising treatment for various cancers; however, the detailed …

Radioactive seed brachytherapy is a method for treating drug‑resistant, late‑stage non‑small
cell lung cancer (NSCLC). To elucidate the mechanism of low‑dose gambogic acid (GA) and …

Aim: Protocatechuic acid (PCA) is one of the common phenolic acids found in many foods
and plants and it has multiple biological activities. Although PCA has been investigated for …

Resistance to conventional chemotherapy is a big challenge in the treatment of cancer
including non-small cell lung cancer (NSCLC). A combination of natural chemo sensitizer …