Internal membrane bound structures sequester all genetic material in eukaryotic cells. The
most prominent of these structures is the nucleus, which is bounded by a double membrane …

The spatial separation of DNA replication and gene transcription in the nucleus and protein
translation in the cytoplasm is a uniform principle of eukaryotic cells. This …

Recent work indicates that the posttranscriptional control of eukaryotic gene expression is
much more elaborate and extensive than previously thought, with essentially every step of …

The transport of RNA molecules from the nucleus to the cytoplasm is fundamental for gene
expression. The different RNA species that are produced in the nucleus are exported …

MicroRNAs (miRNAs) are short RNA gene regulators typically produced from primary
transcripts that are cleaved by the nuclear microprocessor complex, with the resulting …

Nuclear pore complexes (NPCs) are indispensable for cell function and are at the center of
several human diseases. NPCs provide access to the nucleus and regulate the transport of …

Pressure-driven filtration by porous membranes is widely used in the production of drinking
water from ground and surface water,,. Permeation theory predicts that filtration rate is …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

The crystal structures of the ribosome and its subunits have increased the amount of
information about RNA structure by about two orders of magnitude. This is leading to an …

The nuclear envelope is a physical barrier between the nucleus and cytoplasm and, as
such, separates the mechanisms of transcription from translation. This compartmentalization …