[HTML][HTML] Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: a review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …

[HTML][HTML] An Update on the Therapeutic Anticancer Potential of Ocimum sanctum L.: “Elixir of Life”

MR Hasan, BS Alotaibi, ZM Althafar, AH Mujamammi… - Molecules, 2023 - mdpi.com
In most cases, cancer develops due to abnormal cell growth and subsequent tumour
formation. Due to significant constraints with current treatments, natural compounds are …

A comprehensive view on the apigenin impact on colorectal cancer: Focusing on cellular and molecular mechanisms

S Daneshvar, MY Zamanian, MS Ivraghi… - Food Science & …, 2023 - Wiley Online Library
Colon cancer (CC) is one of the most common and deadly cancers worldwide. Oncologists
are facing challenges such as development of drug resistance and lack of suitable drug …

Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis

Y Yang, Y Chen, JH Wu, Y Ren, B Liu… - Phytotherapy …, 2023 - Wiley Online Library
Regulated cell death (RCD) refers to programmed cell death regulated by various protein
molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis …

[HTML][HTML] Recent advancement in bioeffect, metabolism, stability, and delivery systems of apigenin, a natural flavonoid compound: challenges and perspectives

P Chen, F Chen, ZL Guo, J Lei, B Zhou - Frontiers in Nutrition, 2023 - frontiersin.org
Apigenin is a bioflavonoid compound that is widely present in dietary plant foods and
possesses biological activities that protect against immune, cardiovascular, and …

[HTML][HTML] Application of polyphenols and flavonoids in oncological therapy

S Roszkowski - Molecules, 2023 - mdpi.com
The use of naturally derived drugs in anti-cancer therapies has grown exponentially in
recent years. Among natural compounds, polyphenols have shown potential therapeutic …

[HTML][HTML] Mechanism of bile acid-induced programmed cell death and drug discovery against cancer: A review

JY Jang, E Im, YH Choi, ND Kim - International Journal of Molecular …, 2022 - mdpi.com
Bile acids are major signaling molecules that play a significant role as emulsifiers in the
digestion and absorption of dietary lipids. Bile acids are amphiphilic molecules produced by …

[HTML][HTML] Flavonoids as potential antiviral agents for porcine viruses

X Zhang, S Chen, X Li, L Zhang, L Ren - Pharmaceutics, 2022 - mdpi.com
Flavonoids are types of natural substances with phenolic structures isolated from a variety of
plants. Flavonoids have antioxidant, anti-inflammatory, anticancer, and antiviral activities …

[HTML][HTML] Apigenin targets MicroRNA-155, enhances SHIP-1 expression, and augments anti-tumor responses in pancreatic cancer

K Husain, K Villalobos-Ayala, V Laverde, OA Vazquez… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic Cancer (PC) is one of the most lethal cancers. PC promotes the
expansion of immunosuppressive Myeloid-Derived Suppressor Cells (MDSC) and Tumor …

The effect of Apigenin on glycometabolism and cell death in an anaplastic thyroid cancer cell line

S Heydarzadeh, AA Moshtaghie, M Daneshpour… - Toxicology and Applied …, 2023 - Elsevier
Aims and background A more pronounced characteristic of cancer cells is the energy
dependence on glucose, which mitigated by glucose transporters. The comprehension of …