Metformin, a widely prescribed drug for treating type II diabetes, is one of the most
extensively recognized metabolic modulators which has shown an important anti-cancer …

Breast cancer is one of the most common malignancies in females. It is an etiologically
complex disease driven by a multitude of cellular pathways. The proliferation and spread of …

Breast and ovarian cancers are the leading and fifth reason for tumor death among females,
respectively. Recently, many studies demonstrated antiproliferative activities of natural …

For more than 40 years, metformin has been used before and during pregnancy. However, it
is important to note that metformin can cross the placenta and circulate in the developing …

AMP-activated protein kinase AMPK regulates cellular energy by controlling metabolism
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …

This retrospective cohort study investigated whether metformin may reduce gastric cancer
risk by using the reimbursement databases of the Taiwan's National Health Insurance …

We examined whether combinig diclofenac and metformin in doses equivalent to human
doses would synergize their anticancer activity on fibrosarcoma inoculated to hamsters and …

Induced pluripotent stem (iPS) cells share some basic properties, such as self-renewal and
pluripotency, with cancer cells, and they also appear to share several metabolic alterations …

Metformin, a widely used anti-diabetic molecule, has attracted a strong interest in the last 10
years as a possible new anti-cancer molecule. Metformin acts by interfering with …

During the last decade, the burst of interest is observed to antidiabetic biguanide metformin
as candidate drug for cancer chemoprevention. The analysis of the available data have …