Aims Changes in the islet vasculature have been implicated in the regulation of β-cell
survival and function during the progression to type 2 diabetes (T2D). Failure of the β-cell to …

Results: It was noted that combined treatment of 5-FU+ PUFAs on gastric carcinoma (MGC
and SGC) cells produced a significant growth inhibitory action compared with either agent …

Objectives Recent researches have demonstrated good correlation between vascular
endothelial growth factor (VEGF) and diabetic nephropathy (DN); however, this relationship …

Blood vessel networks provide nutrients and gaseous exchange that are essential for
functions. Pancreatic islet capillaries deliver oxygen to endocrine cells while transporting …

Thyroidectomy induces pancreatic edema and immune cells infiltration similarly to that
observed in pancreatitis. In spite of the controverted effects of hypothyroidism on serum …

In diabetes, pancreatic β-cells play a key role. These cells are clustered within structures
called islets of Langerhans inside the pancreas and produce insulin, which is directly …

The heart is the first organ to form during development in vertebrates, and many organs start
to develop adjacent to the cardiovascular system. Endothelial cells (ECs) form the inner cell …

Background Increased serum cystatin C (CysC) can predict the onset of type 2 diabetes
(T2D). Meanwhile, impaired pancreatic α-and β-cell functions get involved in the …

In recent years, strategies targeting β-cell protection via autoimmune regulation have been
suggested as novel and potent immunotherapeutic interventions against type 1 diabetes …

BACKGROUND: Pancreatic islet microvasculature is essential for optimal islet function and
glucose homeostasis. However, islet vessel pathogenesis and its role in the manifestation of …