Synaptic vesicles are organized in clusters, and synapsin maintains vesicle organization
and abundance in nerve terminals. At the functional level, vesicles can be subdivided into …

Exocytosis is a highly regulated process that consists of multiple functionally, kinetically
and/or morphologically definable stages such as recruitment, targeting, tethering and …

Healthy dental enamel is the hardest and most highly mineralized human tissue. Though
acellular, nonvital, and without capacity for turnover or repair, it can nevertheless last a …

Background Abnormal release of neurotransmitters after microwave exposure can cause
learning and memory deficits. This study investigated the mechanism of this effect by …

Background: Mutations in WDR72 have been identified in autosomal recessive
hypomaturation amelogenesis imperfecta (AI). Objective: to describe a novel WDR72 …

BACKGROUND: Several aspects of neurocognitive function have high heritability, but the
molecular genetic mechanisms underlying neurocognition are not known. We performed a …

Goblet cells specialize in producing and secreting mucus with its main component, mucins.
An inducible goblet-like cell line was used for the purification of the mucus vesicles stored in …

Synaptic transmission is dynamic, plastic, and highly regulated. Drosophila is an
advantageous model system for genetic and molecular studies of presynaptic and …

Some forms of idiopathic epilepsy in animals and humans are associated with deficiency of
synapsin, a phosphoprotein that reversibly associates with synaptic vesicles. We have …

Exocytosis of mammalian sperm dense-core secretory granule relies on the same fusion
molecules as all other secretory cells; one such molecule is the small GTPase Rab3A. Here …