An explosion of work over the last decade has produced insight into the multiple hereditary
causes of a nonimmunological form of diabetes diagnosed most frequently within the first 6 …

Hyperinsulinaemic hypoglycaemia (HH) is due to the unregulated secretion of insulin from
pancreatic β-cells. A rapid diagnosis and appropriate management of these patients is …

Neonatal diabetes is a genetically heterogeneous disorder with nine different genetic
aetiologies reported to date. Heterozygous activating mutations in the KCNJ11 gene …

Aim Postnatal hypoglycaemia in newborn infants remains an important clinical problem
where prolonged periods of hypoglycaemia are associated with poor neurodevelopmental …

Hypoglycemia is the result of defects/impairment in glucose homeostasis. The main
etiological causes are metabolic and/or endocrine and/or other congenital disorders …

OBJECTIVE—Mutations in the human HNF4A gene encoding the hepatocyte nuclear factor
(HNF)-4α are known to cause maturity-onset diabetes of the young (MODY), which is …

Assessment of neonatal glycaemic status requires accurate and reliable measurement of
blood glucose concentrations. Most point-of-care technologies are, however, unsuitable for …

Celebrating more than twenty years as the single best source in the field, this Fifth Edition
has now expanded into two cornerstone volumes with 53 fully inclusive chapters and 73 …

Hyperinsulinaemic hypoglycaemia (HH) is characterized by unregulated insulin secretion
from pancreatic β-cells. Untreated hypoglycaemia in infants can lead to seizures …

Objective Activating glucokinase (GCK) mutations are a rarely reported cause of congenital
hyperinsulinism (CHI), but the prevalence of GCK mutations is not known. Methods From a …