Role of adenosine signaling in the pathogenesis of head and neck cancer

R Khayami, Y Toroghian, A Bahreyni… - Journal of cellular …, 2018 - Wiley Online Library
The concentrations of adenosine may increase under ischemic conditions in the tumor
microenvironment, and then it enters the systemic circulation. Adenosine controls cancer …

[HTML][HTML] PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

HS Newton, VS Gawali, AA Chimote… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immunotherapy has emerged as a promising treatment modality for head and
neck squamous cell carcinoma (HNSCC). Pembrolizumab, an anti-programmed death 1 …

Targeted knockdown of the adenosine A2A receptor by lipid NPs rescues the chemotaxis of head and neck cancer memory T cells

HS Newton, AA Chimote, MJ Arnold… - … Therapy-Methods & …, 2021 - cell.com
In solid malignancies, including head and neck squamous cell carcinoma (HNSCC), the
immunosuppressive molecule adenosine, which accumulates in the tumor, suppresses …

The signaling effects of ATP on melanoma-like skin cancer

A Mânica, BSR Bonadiman, AM Cardoso, A Paiz… - Cellular …, 2019 - Elsevier
Melanoma is a type of skin cancer originated by the malignant transformation of
melanocytes. Increasing incidence and mortality require efforts focused on studies and …

Rescue of iCIKs transfer from PD-1/PD-L1 immune inhibition in patients with resectable tongue squamous cell carcinoma (TSCC)

X Huang, J Zhang, X Li, H Huang, Y Liu, M Yu… - International …, 2018 - Elsevier
Objectives The purpose of this study is to evaluate the therapeutic efficacy and the role of PD-
1/PD-L1 pathway in tongue squamous cell carcinoma (TSCC) patients treated with radical …

Curcumin and Vinblastine Disturb Ectonucleotides Enzymes Activity and Promote ROS Production in Human Cutaneous Melanoma Cells

VL Lunkes, TV Palma, CE Assmann… - Brazilian Archives of …, 2022 - SciELO Brasil
Cancer is the leading cause of death. Melanoma skin cancer originates in melanocytes and
represents 80% of the deaths associated with skin cancer. Vinblastine (VIN) is a …

Potassium channels and adenosine signaling in T cells of head and neck cancer patients

HS Newton - 2020 - search.proquest.com
Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common cancer worldwide. Patients with advanced HNSCC have a 50% five-year survival …

[HTML][HTML] Presence and Quantity of COX-2 in Lymph Node Metastases of Patients with Head and Neck Cancer

M Boduc, M Roessler, R Mandic, C Netzer… - … -Head & Neck Surgery …, 2017 - scitemed.com
Presence and Quantity of COX-2 in Lymph Node Metastases of Patients with Head and
Neck Cancer - SciTeMed Publishing Group SciTeMed Publishing Group Search Search …

[PDF][PDF] Presence and Quantity of COX-2 in Lymph Node Metastases of Patients with Head and Neck Cancer

MD Mehtap Boduc, MD Marion Roessler… - Archives of …, 2017 - researchgate.net
Introduction: Cyclooxygenases (COX) catalyze the synthesis of prostanoids from arachidonic
acid, present as two isoforms, namely COX-1 and COX-2. COX-2 has been shown to be …