Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Cancer is a general term for more than 100 unique malignancies in different organs of the
body. Each cancer type and subtype has its own unique genetic, epigenetic, and cellular …

Background Carcinogenesis is governed by a series of genetic alterations and epigenetic
changes that lead to aberrant patterns in neoplastic cells. Sirtuin-1 (SIRT1), an NAD+ …

Simple Summary There are diverse reports of the dual role of sirtuin genes and proteins in
breast and prostate cancers. This review discusses the current information on the tumor …

Spinal cord injury (SCI) is a refractory disease often accompanied by inflammation. Long
non-coding RNA NEAT1 (lncRNA NEAT1) was reported to be involved in the expression of …

Abstract lncRNAs play a vital part in cancer development by regulating gene expression.
Among these, the lncRNA HOTAIR has gained considerable attention due to its …

Background As the most common and detrimental brain tumor with high invasiveness and
poor prognosis, glioblastoma (GBM) has severely threatened people's health globally …

Background Bone metastasis after failure of castration therapy is the main reason of death in
patients with prostate cancer (PCa). Therefore, full awareness of the metastasis mechanism …

Commercial poultry production is associated with various types of stress leading to decrease
of productive and reproductive performance and compromised health of growing chickens …