Quantification of lung PET images: challenges and opportunities

DL Chen, J Cheriyan, ER Chilvers… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

[HTML][HTML] Current applications for nuclear medicine imaging in pulmonary disease

JE Kusmirek, JD Magnusson, SB Perlman - Current Pulmonology Reports, 2020 - Springer
Abstract Purpose of Review The main goal of the article is to familiarize the reader with
commonly and uncommonly used nuclear medicine procedures that can significantly …

[HTML][HTML] Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging

TC Lee, AM Alessio, RM Miyaoka… - The quarterly journal of …, 2016 - ncbi.nlm.nih.gov
Both SPECT, and in particular PET, are unique in medical imaging for their high sensitivity
and direct link to a physical quantity, ie radiotracer concentration. This gives PET and …

Novel outcome measures for clinical trials in cystic fibrosis

HAWM Tiddens, M Puderbach… - Pediatric …, 2015 - Wiley Online Library
Cystic fibrosis (CF) is a common inherited condition caused by mutations in the gene
encoding the CF transmembrane regulator protein. With increased understanding of the …

Variable lung density consideration in attenuation correction of whole-body PET/MRI

HR Marshall, FS Prato, L Deans… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Present attenuation-correction algorithms in whole-body PET/MRI do not consider variations
in lung density, either within or between patients; this may adversely affect accurate …

[HTML][HTML] Advances in PET to assess pulmonary inflammation: a systematic review

L Vass, M Fisk, S Lee, FJ Wilson, J Cheriyan… - European Journal of …, 2020 - Elsevier
Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

[HTML][HTML] Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice

C Dullin, A Svetlove, J Zschüntzsch, F Alves - Scientific Reports, 2022 - nature.com
Retrospective gating (RG) is a well established technique in preclinical computed
tomography (CT) to assess 3D morphology of the lung. In RG additional angular projections …

Advances in microscopy and complementary imaging techniques to assess the fate of drugs ex vivo in respiratory drug delivery: an invited paper

CW Park, YS Rhee, FG Vogt, D Hayes Jr… - Advanced drug delivery …, 2012 - Elsevier
The technical advances in microscopy imaging techniques have been applied to assess the
fate of drugs for researching respiratory drug delivery in ex vivo and in vivo experiments …

[HTML][HTML] In Vivo Micro-CT Assessment of Airway Remodeling in a Flexible OVA-Sensitized Murine Model of Asthma

M Lederlin, A Ozier, G Dournes, O Ousova… - PLoS …, 2012 - journals.plos.org
Airway remodeling is a major pathological feature of asthma. Up to now, its quantification
still requires invasive methods. In this study, we aimed at determining whether in vivo micro …

Application of technetium and rhenium in nuclear medicine

R Alberto - Cosmos, 2012 - World Scientific
Technetium and Rhenium are the two lower elements in the manganese triad. Whereas
rhenium is known as an important part of high resistance alloys, technetium is mostly known …