Lipopolysaccharide (LPS) has been associated with adverse developmental outcomes,
including intra‐uterine fetal death (IUFD) and intra‐uterine growth retardation (IUGR) …

Nitric oxide is a simple free radical with pivotal roles in cell regulation and function (1). The
interaction between nitric oxide and the superoxide radical results in the formation of …

Oxidation of melatonin was followed by measuring chemiluminescence emitted during
pyrrole ring cleavage, a process leading to the main oxidation product of this indoleamine …

d-Galactosamine (GalN) depletes UTP primarily in liver, resulting in decreased RNA
synthesis in hepatocytes. When given together with a sublethal dose of lipopolysaccharide …

Sarcopenia is an age-related condition that involves a progressive decline in muscle mass
and function, leading to increased risk of falls, frailty, and mortality. Although the exact …

Melatonin is known for its radical scavenger activity, which is related to its ability to protect
cells from different kinds of oxidative stress. Oxidative stress has been implicated in the …

Melatonin is a widely-produced and ubiquitously-distributed molecule with multiple critical
functions in all organs and organisms. These functions are mediated by both receptor …

Cycling competitions represent an important physical overload even for well-trained
individuals. In six professional cyclists, we studied the adaptive oxidative and anti …

Recent interest has focused on the use of exogenous melatonin as an antioxidant,
particularly to scavenge the highly cytotoxic hydroxyl radical (HO) which may be generated …

The present review paper supports the approach to deliver melatonin and to target
melatonin receptors for neuroprotection in stroke. We discuss laboratory evidence …