NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

C Jiang, H Huang, X Kang, L Yang, Z Xi… - Chemical Society …, 2021 - pubs.rsc.org
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …

[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action

S Mitra, J Anjum, M Muni, R Das, A Rauf, F Islam… - Biomedicine & …, 2022 - Elsevier
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review

F Herold, A Törpel, L Schega, NG Müller - European Review of Aging and …, 2019 - Springer
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

Therapies for prevention and treatment of Alzheimer's disease

J Mendiola-Precoma, LC Berumen… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …

Sodium benzoate—Harmfulness and potential use in therapies for disorders related to the nervous system: A review

ŁJ Walczak-Nowicka, M Herbet - Nutrients, 2022 - mdpi.com
Currently, due to the large number of reports regarding the harmfulness of food additives,
more and more consumers follow the so-called “clean label” trend, ie, prefer and choose the …

Homocysteine: its possible emerging role in at-risk population groups

E Azzini, S Ruggeri, A Polito - International journal of molecular sciences, 2020 - mdpi.com
Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

M Wang, X Liang, M Cheng, L Yang, H Liu… - Cell death & …, 2019 - nature.com
The elevated level of the amino acid metabolite homocysteine (Hcy) is known as a risk factor
for ischemic stroke. The molecular mechanisms responsible for neurotoxicity of Hcy remain …

Homocysteine and folic acid: risk factors for Alzheimer's disease—an updated Meta-analysis

Q Wang, J Zhao, H Chang, X Liu, R Zhu - Frontiers in aging …, 2021 - frontiersin.org
Background: Recent studies have reported that homocysteine (Hcy) may play a vital role in
the pathogenesis of vascular dementia (VaD) and Alzheimer's disease (AD). Our study …

Early biomarkers of neurodegenerative and neurovascular disorders in diabetes

A Gasecka, D Siwik, M Gajewska… - Journal of Clinical …, 2020 - mdpi.com
Diabetes mellitus (DM) is a common disease worldwide. There is a strong association
between DM and neurovascular and neurodegenerative disorders. The first group mainly …